Celluvisc eye drops contain the active ingredient carmellose sodium (carboxymethyl cellulose), an eye lubricant that increases the tear lipid layer thickness. It prevents the surface of the eye from drying out and reduces dry eye symptoms. More information

A doctor will review your order and write you a prescription, if appropriate. This prescription is then forwarded to a pharmacy. The pharmacy will have your medicine delivered to you within one to three working days. Read more about this process here.

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Patient Leaflet(s)

Celluvisc is a preservative-free tear substitute. The eye drops come in unit dose vials (single-dose units). Each vial of Celluvisc is for single use only. Celluvisc supplements naturally produced tears. This provides soothing relief from the symptoms of dry eyes, such as itching, blurred vision or a gritty sensation. 

What is Celluvisc? 

Celluvisc eye drops contain the active ingredient carmellose sodium (carboxymethyl cellulose), an eye lubricant that increases the tear lipid layer thickness. It prevents the surface of the eye from drying out and reduces dry eye symptoms. Celluvisc eye drops are preservative free to reduce the risk of eye irritation. Lubricating eye drops that add moisture to your eyes to relieve discomfort are also called artificial tears.  

When is Celluvisc used? 

Artificial tears are used to treat the symptoms of dry eyes. The eye has a natural protective moisture layer that protects against dryness and damage. Some people do not produce enough tears to keep the eye wet or produce poor-quality tears. This causes the surface of the eye to dry out, which can lead to the following symptoms: 

  • Itching in the eyes. 
  • A stinging, burning or scratchy sensation in the eyes. 
  • Sensation of pressure or tightness behind the eyes. 
  • Sensitivity to light (e.g. being temporarily blinded by vehicle headlights). 
  • Blurred vision. 
  • Watery eyes. 
  • Damage to the cornea, keratitis (inflammation of the cornea). 

Dry eyes can be caused by various factors, including: 

  • Drying atmospheric conditions (e.g. due to air-conditioning or central heating). 
  • Not blinking sufficiently (e.g. due to computer use). 
  • Sjogren's syndrome, menopause or other conditions that cause mucous membranes to dry up. 
  • Medicine use. Certain medicines can cause dry eyes as a side effect. 
  • Ageing. 
  • Use of contact lenses. 
  • Eye problems, such as chronic inflammation of the eyelids (blepharitis). 

Lubricating eye drops supplement naturally produced tears. This provides soothing relief from the symptoms of dry eyes. Celluvisc eye drops do not cure dry eyes but mimic the effects of natural tears to relieve discomfort. 

Eye drops in multi-dose bottles with a long shelf life contain preservatives. They can cause eye irritation in people who are hypersensitive to preservatives. Celluvisc single-dose units (SDUs) are preservative free. The SDUs can be used by people with sensitive eyes. 

How is Celluvisc used? 

Always use the eye drops as directed by a doctor. The general guidelines for use are as follows: 

  • Wash your hands before using the eye drops. 
  • Celluvisc comes in strips of sterile single-dose units. Each vial is for one-time use only. To use, gently tear one vial from the strip and remove the cap. 
  • Don't let the tip of the vial touch anything, including your eyes, to help prevent contamination. 
  • Stand in front of a mirror and tilt your head backwards. 
  • Gently pull the lower lid of your eye out with one hand to form a pocket. 
  • With the other hand, release one or more drops in the pocket by squeezing the unit. Do not let the tip touch your eye. 
  • Repeat the procedure for your other eye. 
  • Then blink a few times. 
  • Throw away the dose unit immediately after use, even if there is some medicine left in it. Celluvisc does not contain preservatives and therefore each unit is for single use only.  

The eye drops cling to the surface of the eye and provide three to four hours of relief. If dry eyes have caused damage to the cornea, it may take several days for eye irritation to diminish. The artificial tears are suitable for long-term use.  

See the package leaflet for more information on the use of Celluvisc eye drops. 

What doses are available? 

Each single-dose unit contains 0.4 ml of eye drop solution. The solution contains 10 mg carmellose sodium per ml. Always use the drops exactly as your doctor has told you to. General guidelines for use are listed below. 

  • Adults: one to two drops in each eye as needed. 

Safety and effectiveness have not been established in children. Consult a doctor before giving a child the eye drops. 

Consult a doctor if your symptoms do not improve or get worse. 

Read the package leaflet before use. 

What are the side effects of Celluvisc? 

Like all medicines, Celluvisc may cause side effects, although it is generally well tolerated. The following are some of the side effects that have been associated with this medicine: 

  • Mild stinging after putting the drops in. 
  • Temporary blurred vision after putting the drops in. 

These symptoms usually go away after a few minutes. Consult a doctor if the side effects are persistent or if you experience side effects that are not listed on the package leaflet. For more information on side effects, see the package leaflet. 

When not to use Celluvisc? 

Do not use Celluvisc eye drops if:  

  • You are allergic to carmellose sodium or any other ingredient in this medicine (see the package leaflet for a full list of ingredients). 
  • You are wearing contact lenses. Contact lenses should be removed when using this medicine. 

If you are uncertain about whether Celluvisc eye drops are suitable for you, consult a doctor before use. 

Can Celluvisc be used in combination with other medicines? 

Are you using other eye medication such as eye drops or eye ointments? Then the following advice applies: 

  • Administer the other eye medication first. 
  • Wait at least 15 minutes after applying the last eye medication before administering the Celluvisc eye drops. 
  • Always use Celluvisc last. 

If in doubt, contact your doctor or pharmacist. 

Where can I buy Celluvisc? 

Celluvisc eye drops without a preservative are available at pharmacies and online pharmacies. 

Can I buy Celluvisc without a prescription? 

Celluvisc is only available on prescription. You can get a prescription after a consultation (or online consultation) with a doctor.  


Celluvisc package leaflet. (2020, April). Medicines Database. Consulted on 3 July 2020 on https://db.cbg-meb.nl/Bijsluiters/h18218.pdf 

Royal Dutch Pharmaceutical Society. (2019, 19 December). Celluvisc. Apotheek.nl. Consulted on 3 July 2020 on https://www.apotheek.nl/medicijnen/kunsttranen-zonder-conserveermiddel?product=celluvisc#! 

Oogartsen.nl. (n.d.). Dry eyes (keratoconjunctivitis sicca, Sjogren's syndrome). Consulted on 3 July 2020 on https://www.oogartsen.nl/oogartsen/overige_oogziekten/droge_ogen/ 

Dutch National Health Care Institute. (n.d.). Carboxymethyl cellulose. FK Online. Consulted on 3 July 2020 on https://www.farmacotherapeutischkompas.nl/bladeren/preparaatteksten/c/carboxymethylcellulose# 

Assessed by:

Dr Wouter Mol, General practitioner
Registration number: BIG: 9057675501

Dr Wouter Mol studied medicine at the University of Groningen. From 2002 to 2003, he served as a resident in neurology, and from 2003 to 2005 he served his residency training in internal medicine and emergency medicine. Wouter Mol has been working as a GP since 2005.