Clobetasol is a potent steroid medication that helps to reduce instances of inflammation throughout the body. This substance, when applied topically to the skin can help to reduce itching and inflammation caused by things like plaque psoriasis. More information

A doctor will review your order and write you a prescription, if appropriate. This prescription is then forwarded to a pharmacy. The pharmacy will have your medicine delivered to you within one to three working days. Read more about this process here.

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Clobetasol is a prescription drug available as a topical lotion, cream, foam, spray, gel or ointment. In some cases it can also be supplied as a form of shampoo. This substance is available to address various issues with the skin, including psoriasis. Another common form of this medication is sold under the brand name Impoyz.  

What is Clobetasol? 

Clobetasol is a potent steroid medication that helps to reduce instances of inflammation throughout the body. This substance, when applied topically to the skin can help to reduce itching and inflammation caused by things like plaque psoriasis. Clobetasol is also a treatment that's commonly used for skin conditions that will respond well to hormonal and steroid medication.  

Clobetasol topical is used for a variety of reasons, usually to do with the skin. The substance is sold under a range of brand names, which means that you may have used it before without realising it. As a steroid, Clobetasol works on the body by preventing the release of certain substances responsible for inflammation. It was approved by the Food and Drug Administration in 1985.  

When is Clobetasol used? 

This medication, available in many different forms, including creams and gels, is used to treat the discomfort, inflammation and irritation usually caused by psoriasis and plaque psoriasis. Clobetasol can also be used to treat other skin conditions that cause feelings of itching or dry skin.  

In many circumstances, doctors will prescribe Clobetasol as part of a combination treatment solution which means that it may be given alongside a range of other medications. Additionally, Clobetasol belongs to a drug class known as corticosteroids. These medications are used to treat conditions of inflammation by reducing the activity of the immune system. The less your immune system responds to irritants, the less likely it is that you'll suffer from issues like itching and inflammation when suffering from psoriasis.  

How do you use Clobetasol? 

Clobetasol is a topical treatment which is applied directly to the area of skin that suffers from discomfort or inflammation. This substance should never be used on the groin, face, or underarms unless your doctor directs you otherwise. When you begin taking Clobetasol it is important to follow the instructions that are given by your doctor carefully. If you have any questions, ask your pharmacist, or check the patient leaflet provided within your medication packaging for additional information.  

Before you begin using Clobetasol, wash and dry your hands carefully, and make sure that the area that you will be applying the cream or gel to is both clean and dry. Apply a thin layer of the medication to the affected area and rub it in gently, being careful not to harm the skin. Usually, you will be required to apply Clobetasol twice per day to get the full benefits of it. Do not bandage or cover the area that you have applied Clobetasol to unless your doctor tells you to do so. 

If you are using Clobetasol to address the issue of diaper rash in a child, then you should not use plastic pants or tight-fitting diapers on that child. After you have applied the medication, make sure that you wash your hands, unless you are treating the skin on your hands. Be sure that you avoid getting this medication into the eyes, as this can worsen your risk of getting glaucoma. Additionally, it's important not to get Clobetasol into your mouth or nose.  If you get Clobetasol into any dangerous areas, wash the space carefully with plenty of water. Only use this medication for the condition that your doctor prescribes it for, and do not use it for more than 2 weeks in a row unless your doctor advises otherwise.  

What dosages are available? 

Unless your doctor asks you to do something differently, you will often follow the typical dose for Clobetasol. Your dosage will be given based on the condition that you are treating and your response to treatment.  

The common dose for children and adults is usually one thin layer applied to the area of skin that you want to treat twice per day. When the condition begins to improve, your doctor may ask you to begin using this medication less frequently, such as just once a day. Your doctor will determine the duration of your treatment.  

What are the side effects of Clobetasol? 

Serious side effects of Clobetasol are very rare. However, like any medication, it is possible that you will notice unwanted results when you begin using this drug. Some of the most common side effects for Clobetasol will happen in the skin, in the are that you have applied the cream or gel. For instance, you might notice an itching, dryness or redness around the application site. Stinging and burning are also common symptoms. Usually, these responses are a sign that your body is adjusting to the medication, and they will disappear within a few days.  

If the side effects above persist for a long period of time or worsen, then you should speak to your doctor or pharmacist about alternative treatments. Additionally, if you notice any more serious side effects, it's important to seek medical advice as soon as possible. For instance, if you notice skin thinning, acne, discoloration or stretchmarks, this could be a sign of a deeper underlying problem with the way that your body reacts to the medication.  

In some cases, skin infections can become worse when using Clobetasol. If you notice swelling or irritation, then contact your doctor. In rare cases, this substance can also be absorbed into the bloodstream from the skin, which may lead to additional side effects caused by overexposure to a steroid. These side effects are more common in children. Make sure you speak to a doctor if you notice headaches, weight loss, swelling in your feet or ankles, vision problems, increased urination or increased thirst.  Very few people have a serious allergic reaction to Clobetasol. However if your mouth, tongue or throat begins to swell when using this medicine, tell your doctor or seek emergency help. Seek emergency assistance of you have trouble breathing or severe dizziness too.  

When shouldn't you use Clobetasol? 

There are people who will not be suited to taking Clobetasol. Everyone reacts to different medications in their own way. To ensure that your risks with Clobetasol are as low as possible, tell your doctor if you have or have ever had: 

  • Problems with skin thinning 
  • Recent vaccinations 
  • Cushing's syndrome 
  • Acne or rosacea 
  • Diabetes 
  • Skin infections 
  • Chickenpox 
  • Circulation issues 
  • Tuberculosis 
  • Measles 
  • Glaucoma or cataracts 
  • Immune disorders 
  • Problems with intracranial hypertension 

It may be more dangerous for you to use Clobetasol if you continue to use it for an extended period of time. It's not a good idea to use Clobetasol for longer than two weeks, as overexposure to steroids can be dangerous. Using this medication for lengthy periods of time can increase your chances of adrenal gland problems. 

Additionally, remember that this medication can sometimes raise blood sugar levels which means that it may not be suitable for people with unstab;e diabetes. If you have diabetes and your doctor still wants you to take Clobetasol, then you might need to monitor your condition more carefully than usual.  Doctors often avoid giving Clobetasol to children. Although it's unlikely, in very rare cases the medication can sometimes slow a child's growth when used for extended periods of time. Additionally, this drug should not be used during pregnancy unless it is clearly needed. Pregnant women or women who are thinking about getting pregnant should discuss the risks with their doctor.  

Does Clobetasol interact with any other medications? 

There are some medications that may interact negatively with Clobetasol. It's important to speak to your doctor about any drugs that you are taking before you begin using this substance. Arrange an appointment with your doctor where you can discuss all of the medications that you are exposed to, including any over-the-counter drugs or prescription medicines. It's also important to mention any supplements or herbal remedies that you might be taking.  Do not change the drugs you are taking or begin taking a new kind of medication when you're on Clobetasol before speaking to your doctor first. Some of the most common drugs that Clobetasol interacts negatively with include other corticosteroids. Your doctor will want to make sure that you are not over exposed to steroids when using this medication.  

Prednisone can be dangerous to take alongside Clobetasol. Additionally, using this topical cream can cause various other medications to build up in your body to more dangerous levels. When over exposure to steroids happens, the result can be issues with your adrenal glands, Cushing's syndrome and high blood sugar.  

Where can you buy Clobetasol? 

Clobetasol is available from registered online and offline pharmacies provided that you have a prescription to show that your doctor has approved you for this treatment. Make sure that you check the reputation of any pharmacy that you are purchasing this medication from and avoid anyone who does not ask for a prescription or doctor's assessment.  

Can you get Clobetasol without a prescription?  

It is not possible to get Clobetasol in the UK without a prescription. It can be dangerous to take drugs like Clobetasol which include steroids with certain medications and conditions. Your doctor will need to check that this is a suitable treatment for your psoriasis or any other condition before prescribing the medication.  




Cerner Multum, 2019, reviewed by, Clobetasol topical, [Accessed on the 28th of June 2019] Available at: 

RXlist, 2018, online, Consumer Clobetasol Temovate, [Accessed on the 28th of June 2019] Available at:  

University of Illinoise-Chicago Drug information Group, Reviewed April 2018, online, Clobetasol Topical cream, [Accessed on the 28th of June 2019] Available at: 

Assessed by:

Dr Imran Malik, General practitioner
Registration number: GMC: 4741365

Dr Imran Malik studied undergraduate medicine at King's College University in Central London and clinical studies at the prestigious King's College Hospital. He graduated with a MBBS degree in 2000 and went on to gain postgraduate memberships with the Royal Society of Medicine and also General Practice in 2006.