Dymista is a nasal spray with two active ingredients intended to address the symptoms of seasonal allergies and rhinitis. The medication contains Azelastine, which is an antihistamine capable of suppressing allergic reactions and reducing the chances of a patient suffering from issues like running nose, sneezing, and itching. More information

A doctor will review your order and write you a prescription, if appropriate. This prescription is then forwarded to a pharmacy. The pharmacy will have your medicine delivered to you within one to three working days. Read more about this process here.

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Patient Leaflet(s)

Dymista is a combination nasal spray that contains two primary ingredients, fluticasone propionate and azelastine hydrochloride. It's intended to reduce the symptoms of runny or stuffy nose in adults, as well as itching and allergic rhinitis.  

What is Dymista? 

Dymista is a nasal spray with two active ingredients intended to address the symptoms of seasonal allergies and rhinitis. The medication contains Azelastine, which is an antihistamine capable of suppressing allergic reactions and reducing the chances of a patient suffering from issues like running nose, sneezing, and itching. The second component of Dymista is a substance called Fluticasone, which belongs to a group called corticosteroids. The corticosteroid is a synthetic version of the natural adrenal hormone in the body. It works to constrict the blood vessels specifically within the nasal cavity, which reduces inflammation and swelling. When used in spray form, the corticosteroid particularly targets the source of the issue for people who suffer from symptoms of a stuffy noise.  

Used in combination, the two active ingredients in Dymista offer relief from the symptoms of runny and stuffy noses, as well as other complaints common with allergic rhinitis.  

When is Dymista used? 

Dymista is most commonly prescribed for people with seasonal or allergic rhinitis. These conditions cause the patient to experience runny or stuffy nose symptoms, as well as itching, wheezing, sneezing, and problems with breathing through the nose. If you have swelling in your nasal passages caused by rhinitis, then you may also be more prone to snoring and problems with smelling.  

Allergic rhinitis can be caused by a range of issues, including allergies to dust, pets, and even pollen. Sometimes, the symptoms are chronic and last all year around, while other times they only happen at certain times of the year. Dymista is excellent for solving the problems of rhinitis very quickly. After applying the spray, you should begin to notice the difference to your nasal passageways within half an hour or less.  

How do you use Dymista? 

Dymista is very easy to use. However, if this medication is prescribed to a younger child, they may need help from an adult to make sure that they apply the medication to the back of their nostrils properly. You can only use Dymista as a nasal spray, which means you should never take this drug orally. The first time that you use the spray, you will need to prime the pump by pressing it five or six times until you see a light spray appear at the top. You may need to repeat this process if you are using Dymista after a few weeks without using it.  

Before you use the spray, blow your nose gently so you can clear out your nasal passages and get the best coverage for the medication. Tilt your head downwards slightly to apply the spray, gently shaking the bottle and removing the plastic cap before you place the applicator into your nose. Once you have the applicator in one nostril, close the other nostril by pressing the tip of your finger against it gently. Keep the tip of the nasal spray at least a quarter of an inch into your nostril when spraying and keep the bottle upright.  

Press the pump firmly to dispense the medication, and sniff immediately afterwards to draw the medication into the back of your nose. You can tilt your head back for about fifteen seconds to help the medicine disperse across the back of your nose before you repeat the process with the other nostril. After use, wipe the applicator and replace the plastic cap. Avoid getting this medication in your eyes or mouth. If you accidentally expose your eyes to this substance, rinse them with cool water for ten minutes, or until your eyes feel clear.  

What dosages are available? 

A doctor will usually prescribe the correct dose of Dymista based on your response to treatment, your condition, and other crucial factors. It is not recommended to give Dymista to children under the age of 12. The most common dosage of Dymista is one spray per nostril twice a day. Do not take any more or less of this medication than advised by your doctor. Do not take more than required of Dymista if you feel as though you're not seeing results quickly enough. Usually, you will experience results within 30 minutes. Symptoms of Dymista overdose can include thinning skin, increased acne or facial hair, menstrual problems, easy bruising, changes in the location or shape of body fat and loss of sexual drive.

If you're worried that you may have had an overdose of Dymista or you swallow this medication, contact the emergency services immediately. If you miss a dose of Dymista take it as soon as you remember as long as you are not too close to your next scheduled dose time.  

What are the side effects of Dymista? 

Severe side effects of Dymista are rare. However, you should always speak to your doctor or pharmacist if you're concerned about anything that happens to your sense of wellbeing after taking Dymista. Tell your doctor if you experience headaches, nosebleeds, or an unpleasant taste in your mouth, and these symptoms become severe or don't go away.  

Some other side effects that can occur when taking Dymista include: 

  • Problems with vision or eye pain 
  • Severe or ongoing bleeding in the nose 
  • Problems with wounds that don't heal 
  • Drowsiness or extreme fatigue 
  • Muscle weakness 
  • Lightheadedness 
  • Nausea, diarrhea or vomiting 
  • Loss of weight or appetite 
  • Redness, sores or white patches in the mouth 
  • Symptoms of infection like chills, aching or fever 
  • Noisy breathing or a runny nose 
  • Delayed or slowed growth in children 
  • Signs of an allergic reaction 

Dymista often causes feelings of drowsiness because of its antihistamine content. This means that it's always important to use machinery or vehicles with caution when taking this medication.  

When shouldn't you use Dymista? 

There are many different treatments available for seasonal and allergic rhinitis. Dymista may not be the treatment that is suited to you. With that in mind, it's always important to speak to a doctor about your condition before you begin self-treating with Dymista. Tell your doctor about any history of conditions in your family, including issues that effect the eyes like glaucoma or cataracts.  

You should also tell your doctor if you have ever suffered from TB, or any kind of severe infection. Dymista may not work for you if you have had a recent nose injury, sores or ulcers inside of your nasal passageways, or surgery on your nose in the past. This substance may not be ideal for people with diabetes.  

In rare cases Dymista can reduce the number of blood cells in your body available to fight infection. This is a common issue with corticosteroids. With that in mind, your doctor may recommend that you stay away from people who have illnesses or infections when using this medication. You should also inform your doctor immediately if you're exposed to chicken pox, measles or other infectious diseases when using Dymista. It could take several days for your symptoms to begin to improve when using this medication, so speak to your doctor if you don't see results after a week of treatment.  

Dymista is not intended to be used by children under the age of 12 as steroids can cause problems with growth in younger children. You should speak to your doctor carefully about the other options available for your children. Additionally, at this time it isn't known whether Dymista causes significant harm to unborn children. You should speak to your doctor if you're pregnant or planning to become pregnant when using this medication. Doctors are unsure whether Dymista passes into breastmilk, but other corticosteroids do pass into milk. With that in mind, your doctor may recommend avoiding nursing while you're using this drug.  

Does Dymista interact with any other medications? 

It's best to avoid taking depressants like alcohol when you're using Dymista as this can worsen the effects of the drowsiness that often happens in response to an anti-histamine substance. Alcohol may also worsen your risk of other side-effects with Dymista. Remember that this medication contains fluticasone, which is a corticosteroid. Chronic or overuse of corticosteroids can lead to the suppression of the adrenal system, which makes it harder for you to fight off infection and may also cause other significant problems. This component in Dymista may also cause a delay in the healing of wounds and cause a prolonged duration of certain infections. Always tell your doctor about any medications you're taking with Dymista, including recreational drugs, herbal remedies, supplements, over the counter, and prescription medicines. Dymista may interact poorly with:  

  • Lopinavir and ritonavir 
  • Narcotic pain pills 
  • Muscle relaxants 
  • Medications for depression or anxiety 
  • Medications for seizures 
  • Anti-fungal medications 
  • Sleeping pills 

Where can you buy Dymista? 

Dymista is available to purchase from a standard pharmacy. You can ask us to arrange for this medication to be available for collection for you from a registered pharmacy too. We can provide consultations with a registered doctor if you're unsure whether this drug is right for you and your condition. Make sure you follow the instructions provided on the patient leaflet for Dymista. 

Can you get Dymista without a prescription?  

Dymista is available without a prescription. However, it is important to speak with a doctor about your condition before you begin taking this medication, as it can interact poorly with some conditions and medications. Speaking to a registered health professional before you take Dymista will protect you from any severe side effects. Do not self-treat with Dymista without seeking the input of your doctor first.  




Kristin Hayes, RN, 2019, Online, Dymista Uses and Side Effects, [Accessed on 7th of August 2010] Available on: https://www.verywellhealth.com/dymista-azelastine-and-fluticasone-1191814 

Lynn Marks, Medically Reviewed by Sanjai Sinha, Online, 2016, Everyday Health Media, Dymista , [Accessed on 7th of August 2010] Available on: https://www.everydayhealth.com/drugs/dymista  

RXList, Dymista side effects, 2019 Online, [Accessed on 7th of August 2010] Available on: https://www.rxlist.com/dymista-side-effects-drug-center.htm 

Assessed by:

Dr Imran Malik, General practitioner
Registration number: GMC: 4741365

Dr Imran Malik studied undergraduate medicine at King's College University in Central London and clinical studies at the prestigious King's College Hospital. He graduated with a MBBS degree in 2000 and went on to gain postgraduate memberships with the Royal Society of Medicine and also General Practice in 2006.