Emend

Emend is an anti-sickness medicine, also called an antiemetic. It contains the active ingredient aprepitant, which is a neurokinin (NK1) receptor antagonist. Aprepitant prevents the brain’s vomiting centre from being triggered, which helps reduce or prevent nausea. More information

A doctor will review your order and write you a prescription, if appropriate. This prescription is then forwarded to a pharmacy. The pharmacy will have your medicine delivered to you within one to three working days. Read more about this process here.

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Patient Leaflet(s)

What is Emend?

Emend is an anti-sickness medicine, also called an antiemetic. It contains the active ingredient aprepitant, which is a neurokinin (NK1) receptor antagonist. Aprepitant prevents the brain’s vomiting centre from being triggered, which helps reduce or prevent nausea. Emend is available at your local pharmacy or we can order it on your behalf from a registered pharmacy in the EU. For prescription medicines we can also arrange a consultation with a registered EU doctor.

What is this medicine used for?

Cancer treatments, such as radiation therapy or chemotherapy, can cause severe nausea and vomiting. Emend is prescribed to prevent sickness caused by these treatments and is typically used with other medicines. It can also be used to reduce sickness.

How to use Emend

Emend capsules should be swallowed whole with a drink of water. They can be taken with or without food. The capsules are taken one hour before the chemotherapy treatment is started to allow for the active ingredient to be absorbed into the bloodstream. Continue to take this medicine for two days after the last dose of chemotherapy to prevent delayed sickness.

Dosage

Emend is available as 80-mg and 125-mg capsules. Unless otherwise prescribed by your doctor, the usual dose for adults and children aged 12 and above is:

  • Day 1: one 125-mg capsule, one hour before the start of chemotherapy treatment.
  • Day 2 and 3: one 80-mg capsule in the morning.

This medicine is not suitable for children under the age of 12. See the package leaflet for more information on the use of this medicine.

Side effects

Like all medicines, antiemetics can cause side effects. The side effects that are known to be associated with Emend include:

  • Headache.
  • Constipation or disturbances of the gut.
  • Fatigue.
  • Decreased appetite.
  • Hiccups.
  • Increased or decreased amount of liver enzymes in the blood.
  • Dizziness, sleepiness.

Consult your doctor if you have these or other symptoms. For a complete list of side effects, see the package leaflet.

When not to use this medicine

Emend is not suitable for everyone and should not be used if:

  • You are allergic to aprepitant or any other ingredient in this medicine.
  • You are taking certain medicines such as pimozide, terfenadine, astemizole or cisapride.

Emend should be used with caution in people with a decreased liver function. If you have a health condition that is not listed above or are currently on medication, consult a doctor before taking this medicine. It is very important to tell the doctor what medicines or nutritional supplements you are currently taking. For more information on side effects and interactions, see the package leaflet.

Pregnancy/driving ability/alcohol

Do not use Emend if you are pregnant or planning to conceive, unless otherwise instructed by your doctor. This medicine is not recommended in breastfeeding mothers. Emend may cause dizziness or sleepiness. Stay out of traffic if you experience these side effects. This medicine does not interact with alcohol.