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Evista prevents and treats issues of bone loss and bone descaling in women during the menopause. When women go into the menopause stage of their life, they often experience a number of side effects caused by a change to the hormones in their system. More information

A doctor will review your order and write you a prescription, if appropriate. This prescription is then forwarded to a pharmacy. The pharmacy will have your medicine delivered to you within one to three working days. Read more about this process here.

Patient Leaflet(s)

Evista is the brand name of a drug named Raloxifene. This substance is prescribed to women by doctors to prevent and manage bone loss and bone scaling. Usually, it can assist with preventing and reducing osteoporosis after menopause and help bones to remain strong.   

What is Evista? 

Evista prevents and treats issues of bone loss and bone descaling in women during the menopause. When women go into the menopause stage of their life, they often experience a number of side effects caused by a change to the hormones in their system. The most common complaint of women during this transition is that they have weaker and more brittle bones, which can make breaks and fractures more likely. A decrease in estrogen is what makes the bones brittle during menopause. The active substance in Evista, Raloxifene, is a substance that belongs to a group of medications called Selective Estrogen Receptor Modulators. These medications can help to mimic the effects of estrogen in the body, and therefore reduce the side effects of lost estrogen in women. Evista is not a hormone, but it can inhibit and reduce the breakdown of bones, while helping to make bones stronger.  

When is Evista used? 

Evista is not intended as a full treatment for the menopause, because it cannot assist with other symptoms like night sweats and hot flushes. However, this substance is effective at treating osteoporosis and other kinds of bone loss after the menopause takes place. It maintains the density and strengths of bones in the female body, reducing the risk of break or fracture. In some cases, doctors may also prescribe Evista to help prevent against the risk of getting a certain form of invasive breast cancer after menopause. Although Raloxifene isn't a form of estrogen, it can mimic the effects of this hormone in the body. In other parts of the body, such as the breasts and uterus, Evista also acts as an estrogen blocker.  

How do you use Evista? 

Evista tables come in a blister pack of pills that feature calendar dates on them, so you can make sure that you're taking a tablet every day. You will need to take the table at a fixed time each day, as this will help you to get the best results. Read the medication leaflet provided by your doctor or pharmacist before you begin taking Evista, and make sure that you don't take more or less of these tablets than your doctor recommends.  

You can take Evista with or without food, although it's recommended to take them with a glass of water. Make sure that you don't chew the tablet or allow it to dissolve in your mouth. Do not take a double dose of Evista to make up for a missed dose and ensure that you get enough lime and vitamin D into your diet when you're taking this pill. A doctor giving you Evista may request that you take calcium and vitamin D tablets to ensure that you maintain a good quality of life while using the pills. Because this medication can be absorbed through the lungs and skin, it could potentially harm an unborn baby. With that in mind, women who may become pregnant when using Evista are not recommended to use this medication. Your doctor will generally only prescribe this drug if you are no longer capable of getting pregnant.  

What dosages are available? 

Your doctor will tell you which dose of Evista to take based on your condition. The most common dose is 1 tablet per day. Each single tablet of Evista contains approximately 60mg of Raloxifene. Make sure that you follow the instructions given by the doctor. Remember, if you miss a dose of Evista it is important to take it as soon as you remember. However, if you are close to the time of your next dose, skip the missed dose completely and take your next pill at the usual time.

What are the side effects of Evista? 

All medications, including Evista can sometimes cause side effects. It's important to be aware of these side effects before you begin taking the medication. If you notice anything that isn't on this list, or you're concerned about your health after taking Evista, make sure that you contact an emergency health professional. If any of the following dangerous side effects occur, you must stop taking this drug immediately and seek emergency attention: 

  • Severe migraine headache 
  • Coughing blood 
  • Loss or change in speech 
  • Loss or change in vision 
  • Loss or change in coordination 
  • Numbness or pain in chest, leg or arm 
  • Shortness of breath 
  • Bloody urine 
  • Chest pain or difficulty breathing 
  • Burning or painful urination 

There are some more common side effects that are associated with Evista which may go away on their own. These include fever, a frequent urge to urinate, infection in the body, leg cramping, rash somewhere on the skin, swelling of the ankles, feet or hands, or vaginal itching. If these conditions do not get better, or worsen, seek the advice of your doctor. You may also notice abdominal pain, aching body issues, loss of appetite, nausea, trouble swallowing, weakness, difficulty with decreased vision, hoarseness of voice, or diarrhea.  

There are also side effects associated with Evista that do not require medical attention. Usually, these side effects will diminish naturally during your treatment, and they will just be a sign of your body adjusting to the medication. However, if you are ever concerned about any response your body has to a medicine, you can talk to a healthcare professional or pharmacist. The most common symptoms of Evista include: 

  • Trouble sleeping 
  • Unexplained weight gain 
  • Swollen joints 
  • Problems with gas 
  • Upset stomach 
  • Vomiting 
  • Depression 
  • Muscle or joint pain 
  • Increased vaginal discharge 
  • Increased hot flashes 

When shouldn't you use Evista? 

Evista is only one of many available treatments used to manage issues of bone loss and descaling in patients with the menopause. Your doctor will conduct a full medical review with you to make sure that the drug you're taking is right for you and your background. With that in mind, it's important to tell your doctor about your full medical history, as well as any symptoms that you're currently having during the menopause. It should not be used with people with a history of endometrial cancer, liver or renal failure. 

This medication can increase the risk of blood clots in some people - particularly if you spend a lot of time off your feet. You will need to tell your doctor if you have ever had a blood clot in your lungs, legs, or you have ever had a stroke. If you will be off your feet for any period of time when taking Evista, perhaps because you're having surgery, tell your doctor. Patients on bed rest will usually be asked to stop taking Evista temporarily as their risk of blood clots will be increased.  

Tell your doctor if you have a history of kidney or liver disease, as well as if anyone in your family have had these conditions. You will also need to tell your care professional if you may be pregnant before you begin this treatment. Evista and Raloxifene is not suitable for a pregnant woman or any woman who intends to become pregnant. It is not a good idea to breastfeed when using Evista. Typically, your doctor will recommend against nursing if you are using any medication for hormone replacement, as these drugs can pass through the skin and into the blood.   

Does Evista interact with any other medications? 

Whenever you begin taking a new medication, it is important to tell your doctor about all of the existing substances that you are exposed to. This includes recreational drugs, even if they're illegal. Make sure that you tell your doctor about over the counter medications that you're taking, and prescription drugs. Additionally, it's important to discuss any herbal medications or supplements, as these can all have an impact on the way that Evista works.  

Because your chances of getting a blood clot can be a little higher with Evista, it's usually not a good idea to take this medication with aspirin or drugs containing aspirin unless your doctor recommends otherwise. Additionally, some studies suggest that acid-binding resins can interact negatively with Evista. These drugs include colestipol and cholestyramine. Do not take Evista with other estrogen-based medications. In some cases, this drug may interfere with the results on certain laboratory test, which leads to false test results. Make sure that all of your doctors are aware that you're using this drug before you are exposed to any tests.  

Where can you buy Evista? 

Evista should be available to purchase from any typical online or offline pharmacy. It is not available over the counter, although you may be able to arrange for this medication to be prepared ready for you to collect after you have received a prescription. We can offer you a consultation with a registered healthcare professional to help you speed up the process.  

Can you get Evista without a prescription?  

Evista will not be suitable for everyone suffering from side-effects as a result of the menopause. You will need to speak to your doctor about your conditions and symptoms to ensure that this medication is safe for you. Evista is not available without a prescription due to the nature of the medication. Your doctor will need to conduct a complete medical review to ensure that you are well suited to this drug. Do not attempt to self-treat any condition with Evista without a doctor's advice.  




Drugs.com, Online, 2019, Raloxifene Side Effects, [Accessed on 8th of August 2019], Available at: https://www.drugs.com/sfx/raloxifene-side-effects.html 

EMedicine Health, Online, 2019, Raloxifene, [Accessed on 8th of August 2019], Available at: https://www.emedicinehealth.com/drug-raloxifene_oral/article_em.htm  

IBM Micromedex, Online, 2019, Mayo Clinic, Raloxifene Oral Route, [Accessed on 8th of August 2019], Available at: https://www.mayoclinic.org/drugs-supplements/raloxifene-oral-route/side-effects/drg-20065760 

Assessed by:

Dr Imran Malik, General practitioner
Registration number: GMC: 4741365

Dr Imran Malik studied undergraduate medicine at King's College University in Central London and clinical studies at the prestigious King's College Hospital. He graduated with a MBBS degree in 2000 and went on to gain postgraduate memberships with the Royal Society of Medicine and also General Practice in 2006.