Femodene is a combined contraceptive pill. The combined contraceptive pill is referred to as such because it contains two types of hormones, progestogen, and estrogen. The versions of these hormones in Femodene are synthetic, but they work the same way in your body as the usual hormones, stopping your body from ovulating so that you don’t get pregnant. More information

A doctor will review your order and write you a prescription, if appropriate. This prescription is then forwarded to a pharmacy. The pharmacy will have your medicine delivered to you within one to three working days. Read more about this process here.

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Femodene is a form of hormonal contraceptive frequently referred to as the combined contraceptive pill, or the combined oral contraceptive “COC”. These tablets are called the combined pill because they contain two active ingredients – gestodene, and ethinylestradiol.  

What is Femodene? 

Femodene is a combined contraceptive pill. The combined contraceptive pill is referred to as such because it contains two types of hormones, progestogen, and estrogen. The versions of these hormones in Femodene are synthetic, but they work the same way in your body as the usual hormones, stopping your body from ovulating so that you don’t get pregnant.  

Femodene can also help to prevent pregnancy in other ways. For instance, it will stop the lining of your womb from supporting a fertilized egg and increase the mucus in the cervix.  

When taken properly, Femodene like other combined contraceptive is a very effective way to protect against pregnancy. You can also stop taking this pill at any time if you decide that you do want to try and have a baby. However, it is important to keep in mind that this pill will not protect you from a sexually transmitted infection or disease. You will need to seek other forms of contraception if you believe that you are at risk.  

When is Femodene used? 

Femodene is used most commonly to help women protect themselves against the risk of an unwanted pregnancy. Combined pills like Femodene are also occasionally prescribed for women who have issues with particularly painful or heavy periods. Taking this medication regularly will usually result in less painful and lighter periods, as well as more regular bleeding. 

How do you use Femodene? 

Femodene is different to most combined pills, which requires a seven day period without any medication at all. When you take Femodene you will need to use it every day without any break. There are 7 pills included in your strip which do not include any active ingredients or hormones. These are to be followed immediately by the inactive pills when you’re done with your monthly strip.  

When taking Femodene, it’s important to follow the instructions provided on the packet carefully, or you may not be fully protected against pregnancy. Take each pill with a glass of water and try to set a routine that allows you to take your pill at the same time each day.  

Taking the pill at the same time every day will keep your hormone levels consistent and reduce your risk of side effects. If you begin using Femodene in the first five days of your menstrual cycle, you will be protected from pregnancy immediately. If you begin using this pill at any other point in your menstrual cycle, you will need to use a different form of contraceptive for seven days.  

What dosages are there? 

Femodene comes in a packet with a monthly dose of 21 active tablets included, followed by seven placebo tablets. You need to take a pill every day at the same time to protect yourself against pregnancy. It is important to follow the markings on the packets to ensure that you don’t accidentally take a placebo pill when you are supposed to be using an active pill, and vice versa.  

Follow the instructions provided by your consultant and ask for advice if you are concerned. Remember that you may experience a withdrawal bleed similar to a regular period during the week when you are not taking Femodene. However, during this time, you should still be protected against pregnancy.  

Femodene must be taken at the same time every day. If you forget to take a pill, you can take it as soon as you remember, unless you are due your next dose. If you miss one pill you may not be protected against pregnancy andit may be a good idea to use other barrier forms of protection until you have taken 7 active days of pill. It is also important to speak to your doctor about whether you are still protected from pregnancy if you suffer from diarrhea or sickness. These problems can stop Femodene from being fully absorbed into your system.  

What are the side effects of Femodene? 

Femodene and other forms of the combined pill rarely cause any severe side effects. However, different people respond to medications in different ways. You will need to make sure that you read the patient leaflet carefully to ensure that you are taking Femodene correctly, and that you are aware of the side effects that you might encounter.  

The most common side effects associated with Femodene often happen when you are in the first few months of taking your medication. This can happen because your body is getting used to the new dose of hormones, and the side effects should settle on their own. Common side effects include: 

  • Sore or painful stomach; 
  • Bleeding or spotting between periods; 
  • Weight gain or water retention; 
  • Tender or uncomfortable breasts; 
  • Mood swings; 
  • Headaches. 

Femodene may occasionally cause some less common side effects, such as nausea, stomach pains, migraines, or a severe headache. Femodene can also cause problems with your libido. If you concerned about these side effects, it is best to speak to a doctor about whether you should continue to take Femodene. Additionally, you should see a doctor if you experience: 

  • Signs of an allergic reaction, like swelling around the lips, tongue, mouth, throat, or hands, and difficulty swallowing or breathing; 
  • Signs of blood clots in your artery or vein. This could present in the form of swelling in the leg, changes in the colour of your legs, unexpected problems with breathlessness, or chest pains and dizziness; 
  • Signs of breast changes such as lumps or dimpling of the skin, or changes in your nipple; 
  • Signs of cervical cancer, including unusual and unexplained vaginal bleeding and discharge, or pain in your pelvis; 
  • Signs of liver issues, such as problems with your upper abdomen being painful, yellowing in the eyes or skin, and inflammation of the liver.  

Femodene can cause some withdrawal bleeding during the seven days when you’re not taking any of the active ingredient tablets. Additionally, Femodene can cause your bleeding to be lighter, less painful, and more regular.  

When shouldn’t you use Femodene? 

Though many women will respond well to the combined contraceptive pill, like Femodene, it’s important to note that this medication will not be suitable for everyone. When you are having your consultation, it’s important to answer any questions that your consultant might have and ensure that you provide your consultant with information about your medical history. 

Generally, Femodene should not be given to women who are over the age of 35 and smokers. Additionally, you will not be prescribed this medication if you are very overweight, and you have ever suffered with blood clots in your legs or your lungs. Other people who may not be able to take Femodene, include: 

  • People who have had a heart attack, stroke, or angina; 
  • People with very high blood pressure or vascular disease; 
  • People with heart valve issues or an irregular heartbeat; 
  • People with blood disorders that increase their risk of blood clots; 
  • People with severe diabetes including complications that affect the eyes; 
  • People who suffer from a migraine with aura; 
  • People with breast cancer or who have had breast cancer in the last five years; 
  • People with liver disease, or liver cancer; 
  • People with gallbladder disease; 
  • People with jaundice or a hearing disorder; 
  • People with porphyria. 

There are cases where your consultant or doctor may need to consider the risks and benefits of giving you Femodene carefully if you have certain conditions. For instance, you may still be able to take Femodene if you have diabetes, but you will need to monitor your blood sugar levels carefully. You can also continue to take this medication in some cases if you have high cholesterol levels or high blood pressure, as long as you monitor the issue carefully.  

In some cases, Femodene will need to be prescribed on a basis where your doctor regularly requests appointments with you to check how well you are responding to the medication. This is usually the case if you haver issues that have affected your blood flow or your menstrual cycle in the past. Because Femodene can increase your risk of blood clots, you will need to be extra careful about protecting against blood clots. If you travel frequently, you will need to speak to a doctor about improving your circulation while you travel.  

Does Femodene interact with other medications? 

Femodene is not the right method of contraception for all women. You will need to speak to your consultant about your condition, as well as any other medications that you are using with Femodene. Some medications, including prescription pills, over the counter drugs, and even herbal remedies can affect the way that your body responds to Femodene. Sometimes, these medications will make your contraceptive less effective.  

Some examples of medication that effect the effectiveness of Femodene: 

  • Antiepileptic medications like perampanel and primidone; 
  • Medicines for HIV like nevirapine or cobicistat; 
  • Medications for antifungal treatments like griseofulvin; 
  • Medications intended for narcolepsy treatment like modafinil; 
  • Antibiotics like rifampicin and rifabutin for tuberculosis; 
  • Herbal remedies like St John’s Wort. 

If you are given a short course of any of the medications above, then your doctor may allow you to continue to take Femodene although you may need to use another form of contraceptive at the same time. Most antibiotics will not affect the way that the combined contraceptive pill works. However, if you are taking a contraceptive pill with antibiotics and you are concerned, use other methods of protection.  

Where can you buy Femodene? 

Femodene is available to buy safely online after a consultation with one of our professionals, you will need to submit a recent blood pressure reading. We can send a prescription for you to a local pharmacy within 3 working days.  

Can I get Femodene without a prescription? 

Femodene and other combined contraceptive pills are currently not available without a prescription.  


Drugs.com, 2019, online, “COLOFAC 135MG TABLETS” [Accessed 18th of December 2019], Available on: https://www.drugs.com/uk/colofac-135mg-tablets-leaflet.html 

Medicines.org, online, 2019, “Colofac 135 mg Tablets”, [Accessed 18th of December 2019], Available on: https://www.medicines.org.uk/emc/product/1166/pil  

Medsafe, online, 2019, “Mebeverine hydrochloride tablets 135mg” [Accessed 18th of December 2019], Available on: https://www.medsafe.govt.nz/consumers/cmi/c/colofac.pdf 

Assessed by:

Dr Imran Malik, General practitioner
Registration number: GMC: 4741365

Dr Imran Malik studied undergraduate medicine at King's College University in Central London and clinical studies at the prestigious King's College Hospital. He graduated with a MBBS degree in 2000 and went on to gain postgraduate memberships with the Royal Society of Medicine and also General Practice in 2006.