Femseven can no longer be ordered. In the category Hormone Replacement Therapy (HRT) you will find alternatives.

FemSeven

Femseven

Femseven is part of a range of treatments called Hormone Replacement Therapies designed to help women cope with the side effects of going through the menopause.  When the menopause happens your ovaries stop producing oestrogen, causing  a drop in the amount of oestrogen in your body and this can lead to a variety of unpleasant symptoms including:  hot flushes  low libido  frequent urinary tract infections  mood swings  night sweats  difficulty sleeping  headaches  anxiety  Some women may be able to cope with these symptoms by making a few simple lifestyle changes:  exercising for 30 minutes a day at least 5 times a week;  eating a well-balanced diet with plenty of nutrients;  dressing in comfortable layered clothing, so you can remove a layer if need be;  maintaining a healthy lifestyle;  limiting alcohol intake;  losing excess weight;  taking a cool shower;  opening windows when possible;  avoiding caffeine and spicy food. More information

A doctor will review your order and write you a prescription, if appropriate. This prescription is then forwarded to a pharmacy. The pharmacy will have your medicine delivered to you within one to three working days. Read more about this process here.

Patient Leaflet(s)

​​The menopause is a natural process for women and usually happens between the ages of 45 to 55, often it brings with it a range of rather unpleasant side effects like hot flushes, difficulty sleeping, lower sex drive and irritability to name just a few. For some women, a few simple lifestyle changes can help them to cope during these times, for others life becomes unbearable. Fortunately, there are a variety of Hormone Replacement Therapies available to help, from creams to pills to patches and more, some target specific side effects of menopause and others cover a whole range. Some contain both oestrogen and others contain oestrogen and progesterone. Finding the right HRT for you can be a process of trial and error but arranging an in-depth consultation with a doctor is a good way to start the process.  

What is Femseven? 

Femseven is part of a range of treatments called Hormone Replacement Therapies designed to help women cope with the side effects of going through the menopause. 

When the menopause happens your ovaries stop producing oestrogen, causing  a drop in the amount of oestrogen in your body and this can lead to a variety of unpleasant symptoms including: 

  • hot flushes 
  • low libido 
  • frequent urinary tract infections 
  • mood swings 
  • night sweats 
  • difficulty sleeping 
  • headaches 
  • anxiety 

Some women may be able to cope with these symptoms by making a few simple lifestyle changes: 

  • exercising for 30 minutes a day at least 5 times a week; 
  • eating a well-balanced diet with plenty of nutrients; 
  • dressing in comfortable layered clothing, so you can remove a layer if need be; 
  • maintaining a healthy lifestyle; 
  • limiting alcohol intake; 
  • losing excess weight; 
  • taking a cool shower; 
  • opening windows when possible; 
  • avoiding caffeine and spicy food. 

However, for some, the symptoms of menopause can drastically affect their ability to lead a normal life. For these women, it is likely an HRT will be prescribed. it is always worth trying these changes even if you are taking an HRT 

Femseven is one such HRT, it contains the active ingredient oestradiol hemihydrate, a female oestrogen which helps to balance the hormones in your body, reversing the drop in natural oestrogen and in turn alleviating some of the unpleasant effects of the menopause. 

When is Femseven used? 

Femseven is used to combat the symptoms of menopause when they are seriously affecting your ability to lead a normal life. 

  • Femseven is usually prescribed for women who have undergone a hysterectomy; 
  • If you have not had a hysterectomy you will need to take some kind of progesterone alongside using Femseven to help prevent problems with the womb lining; 
  • Femseven is also used to ward off osteoporosis where other treatments may be unsuitable. 

How do you use Femseven? 

Femseven comes as a transdermal patch. This is a sticky patch that is applied to the skin below the waist and left in place for seven days. The medication is contained within the sticky part of the patch and will gradually be released over the course of the seven days. (The rate is 50 micrograms every twenty-four hours for Femseven 50, 75 micrograms every twenty-four hours for Femseven 75 and so on.) 

To apply your patch: 

  • Carefully remove the individual patch from its packet; 
  • Peel off half of the protective backing at the ‘S-shaped’ notch; 
  • Avoid touching the adhesive side of the patch with your fingers as this may affect its ability to stick and stay in place; 
  • Decide where to place the patch, below the waist, avoid areas where it may rub against clothing (like your waist) opt for a place where it is more likely to stay in place like your buttocks, hips or abdomen, also avoid any red or broken skin or oily patches; 
  • Remove the other half of the protective backing and press the patch firmly against your skin with the palm of your hand for at least 30 seconds; 
  • The warmth of your skin will help to fix the patch in place; 
  • Once in place you can shower, swim and exercise as normal; 
  • After 7 days you will need to remove the patch and apply another: 
  • Lift off one edge of the patch and pull it off; 
  • Fold the patch sticky sides together (to prevent any leftover medication from escaping); 
  • Throw away in your normal rubbish bin; 
  • Apply a new patch in a different location. 

If your patch comes off before the seven days are up then you will need to apply a new patch in a different location. Once applied you leave this replacement patch in place for seven days and then continue the seven-day cycle as normal. 

What dosages are there? 

Femseven patches come in 3 different strengths: 

  • 50 micrograms 
  • 75 micrograms 
  • 100 micrograms 

All of the patches are worn for seven continuous days before changing for a new patch. The release the number of micrograms mentioned on the pack continuously over the space of 24-hours. For example, Femseven 50 releases 50 micrograms of estradiol hemihydrate per 24 hours. 

There are no breaks or rest periods with Femseven, you switch each patch with the next. 

With all HRTs you should aim to take the lowest possible dose for the shortest possible time. Your doctor will decide which dose is most suitable for you, you may need to adjust the dose once you start if you find you can take a lower dose or need a higher one. 

What are the side effects of Femseven? 

As with all medication, Femseven comes with the risk of some side effects, not everyone using Femseven will get them. 

The following diseases have been reported more often in women using HRT compared to women not using HRT: 

  • ovarian cancer; 
  • cancer of the lining of the womb or abnormal growth in the womb; 
  • breast cancer; 
  • heart disease; 
  • stroke; 
  • blood clots;
  • loss of memory.

The most common side effects are: 

  • eczema
  • itching; 
  • red skin; 
  • urticaria; 
  • swelling (oedema);
  • changes to the skin’s pigmentation.

Usually, these reactions are mild and disappear a few days after the patch has been removed. 

The following side effects occur in up to 1 in 10 people: 

The following side effects occur in up to 1 in 100 people: 

  • joint pain;
  • leg cramps;
  • increased sweating; 
  • hair loss or increase;
  • dizziness; 
  • migraine; 
  • tingling in fingers or toes; 
  • anxiety; 
  • depression;
  • increased appetite; 
  • insomnia; 
  • nausea;
  • indigestion; 
  • abdominal pain; 
  • chest pain; 
  • blood pressure increase or decrease;
  • swelling; 
  • change in weight;
  • tiredness;
  • vein disorders; 
  • breakthrough bleeding; 
  • vaginal discharge. 

The following side effects may occur in up to 1 in 1,000 people: 

  • worsening benign growths in the womb (uterine fibroids) 

If you experience serious side effects then speak to your doctor or pharmacist. 

When shouldn’t you use Femseven? 

If you have or have ever had any of the following then you should not use Femseven: 

  • breast cancer; 
  • any cancer sensitive to oestrogens (for example, cancer of the womb lining); 
  • unexplained vaginal bleeding; 
  • a blood clotting disorder; 
  • a recent disease caused by blood clots in the arteries like a recent heart attack, stroke or angina; 
  • a blood clot in a vein; 
  • liver disease; 
  • excessive thickening of the womb lining; 
  • a rare blood problem called porphyria; 

if you are allergic to estradiol hemihydrate or any of the other ingredients listed on the packet. 

If you experience any of the conditions listed above for the first time while using Femseven then you should stop the treatment and seek immediate medical assistance. 

If you have ever had any of the health issues listed below you should discuss this carefully with your doctor before starting treatment with Femseven as you may require more frequent check-ups: 

  • growth of the womb lining outside your womb; 
  • a history of abnormal growth of the womb lining; 
  • fibroids inside your womb; 
  • increased risk of developing blood clots; 
  • increased risk of getting oestrogen-sensitive cancer; 
  • high blood pressure; 
  • gallstones; 
  • diabetes; 
  • migraine or severe headaches; 
  • asthma
  • epilepsy; 
  • hereditary angioedema; 
  • fluid retention due to cardiac or kidney problems; 
  • a disease of the immune system that affects many organs in the body (systemic lupus); 
  • a disease affecting the eardrum and hearing; 
  • a very high level of fat in your blood. 

Does Femseven interact with other medications? 

Always discuss any medication you are currently taking with your doctor, even herbal remedies and supplements as these may interfere with the effect of Femseven and could cause issues like irregular bleeding, some examples of more common drugs that interact: 

  • medicines for tuberculosis; 
  • medicines for HIV
  • medicines for epilepsy; 
  • herbal remedies containing St John’s Wort. 

Where can you buy Femseven? 

You can buy Femseven from any reputable pharmacy, take your pick from those available to you. Pop into your local pharmacy or supermarket pharmacy or order online for delivery at your convenience, a recent blood pressure reading will be needed. 

Can I get Femseven without a prescription? 

No, you cannot purchase Femseven without a prescription. Hormone Replacement Therapies require careful monitoring and come with a warning of serious side effects and risks so you will need frequent checkups throughout your treatment. You can visit your regular surgery or arrange an online consultation with a doctor to discuss your medical history and decide on the right Hormone Replacement Therapy for you. 

Sources 

Brazier, Y. (2017). Hormone replacement therapy: Uses, types, and alternatives. [online] Medical News Today. Available at: https://www.medicalnewstoday.com/articles/181726.php#types [Accessed 7 Jan. 2020]. 

NHS (2019). Hormone replacement therapy (HRT). [online] nhs.uk. Available at: https://www.nhs.uk/conditions/hormone-replacement-therapy-hrt/ [Accessed 7 Jan. 2020]. 

NHS UK (2018). Menopause - Treatment. [online] nhs.uk. Available at: https://www.nhs.uk/conditions/menopause/treatment/ [Accessed 7 Jan. 2020]. 

Teva Pharmaceuticals Europe (2017). FEMSEVEN 50 | Drugs.com. [online] Drugs.com. Available at: https://www.drugs.com/uk/femseven-50-leaflet.html [Accessed 7 Jan. 2020]. 

Assessed by:

Dr Imran Malik, General practitioner
Registration number: GMC: 4741365

Dr Imran Malik studied undergraduate medicine at King's College University in Central London and clinical studies at the prestigious King's College Hospital. He graduated with a MBBS degree in 2000 and went on to gain postgraduate memberships with the Royal Society of Medicine and also General Practice in 2006.