Granisetron

Granisetron is used to prevent and treat nausea and vomiting caused by chemotherapy or radiotherapy treatment. This medicine is available in tablet form. You can buy Granisetron at your local pharmacy or we can order it on your behalf from a registered pharmacy in the EU. More information

A doctor will review your order and write you a prescription, if appropriate. This prescription is then forwarded to a pharmacy. The pharmacy will have your medicine delivered to you within one to three working days. Read more about this process here.

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Patient Leaflet(s)

What is Granisetron?

Granisetron is used to prevent and treat nausea and vomiting caused by chemotherapy or radiotherapy treatment. This medicine is available in tablet form. You can buy Granisetron at your local pharmacy or we can order it on your behalf from a registered pharmacy in the EU. For prescription medicines we can also arrange a consultation with a registered EU doctor.

What is this medicine used for?

Cancer treatments, such as radiotherapy and chemotherapy, can cause severe nausea and vomiting. Granisetron can be used to prevent or treat these symptoms. The active ingredient granisetron is a type of medicine called a 5HT3 (serotonin) antagonist. Granisetron works by blocking the 5HT3 receptors that are found in the brain and gut. This prevents nausea messages being sent from these areas to the vomiting centre in the brain. Granisetron is given right before chemotherapy or radiotherapy treatment is started to prevent nausea and vomiting. It can also be used to reduce acute nausea.

How to use Granisetron

Granisetron is available in tablet form. To prevent nausea, the tablets should be taken with some water approximately one hour before treatment. To prevent delayed sickness, continue to take this medicine for no more than seven days after the last dose of chemotherapy or radiotherapy. You can take this medicine straight away if you feel nauseous already.

Dosage

Unless otherwise prescribed by a doctor, the usual dose is:

  • one 2-mg tablet once a day or one 1-mg tablet twice a day for a maximum of seven days.

Granisetron is intended for use in adults only. See the package leaflet for more information on the use of this medicine.

Side effects

Granisetron may cause side effects, although some people may not experience any. The most common side effects are:

  • Headache.
  • Constipation or diarrhoea.
  • Insomnia.
  • Hepatic impairment.
  • Rash.

Consult a doctor if you experience these or other side effects. See the package leaflet for more information on the possible side effects.

When not to use this medicine

Granisetron is not suitable for everyone. Do not use this medicine if you are allergic to granisetron or any other ingredient in this medicine. People with intestinal obstruction or constipation, heart disease, abnormal levels of electrolytes in their blood or who are being treated with medications that can have side effects on the heart should use Granisetron with caution. Consult a doctor on the use of Granisetron if you have other health problems. Granisetron may interact with certain medicines. Therefore, it is important to tell the doctor what medicines you are currently taking to make sure the combination is safe. See the package leaflet for more information about contraindications and interactions.

Pregnancy/driving ability/alcohol

Do not use Granisetron if you are pregnant or breastfeeding, unless otherwise advised by your doctor. Granisetron does not affect your ability to drive safely or interact with alcohol.