Metosyn is an anti-inflammatory corticosteroid that can be applied topically to the skin. The ointment and cream version of this medication contain the active ingredient fluocinonide, which is effective at reducing the symptoms of issues like itching and pain. More information

A doctor will review your order and write you a prescription, if appropriate. This prescription is then forwarded to a pharmacy. The pharmacy will have your medicine delivered to you within one to three working days. Read more about this process here.

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Metosyn is a type of anti-inflammatory medication, used topically on the skin. This medication can be used in a wide range of different purposes. Metosyn includes an active ingredient called fluocinonide, which is a very potent corticosteroid.  

What is Metosyn? 

Metosyn is an anti-inflammatory corticosteroid that can be applied topically to the skin. The ointment and cream version of this medication contain the active ingredient fluocinonide, which is effective at reducing the symptoms of issues like itching and pain. Metosyn can reduce inflammation when it is caused by irritation or allergies. When the skin is irritated, it causes the release of crucial immune system substances which cause blood vessels to widen. 

When blood vessels widen, the irritated area becomes itchy, swollen and painful. When you apply Metosyn to the skin it acts inside the skin cells to reduce the release of inflammatory substances. The Metosyn can reduce swelling and redness. There are a range of different kinds of corticosteroids which can be used for a similar affect. However, Metosyn is quite potent, usually recommended when other treatments do not work.  

Metosyn creams can be more suitable for conditions where there may be weeping or moist areas of skin. Alternatively, if you are given the ointment version of this medication then it may be better for dry and scaly parts of skin.  

When is Metosyn used? 

Metosyn is used for the treatment of various forms of inflammation in the skin. Often, this medication is suitable for treating weeping skin and other issues that cannot be supported by different forms of corticosteroid. Metosyn in both ointment and cream form can be ideal for the treatment of dermatitis and eczema, as well as inflammatory skin conditions with red and scaly areas.  

You may be given Metosyn for a thickened skin rash that may have been caused by excessive scratching. If so, this medication will reduce itching and other symptoms. Metosyn is excellent for psoriasis, and skin disorders like lupus erythematosus, which can occur when the immune system attacks the skin. Metosyn works well for areas where there are itchy shiny patches of skin.  

How do you use Metosyn? 

Ask your consultant about any questions that you may have regarding the use of Metosyn. If you are worried about using Metosyn, then you should read the patient leaflet provided when you receive this medication. The leaflet will include information on how to use Metosyn, as well as how you may be able to avoid certain side effects with this medication.  

Your doctor will advise you on whether this treatment is correct for you and should be avoided in infected skin. 

Metosyn is a form of topical treatment that needs to be applied thinly to the affected skin areas twice or once a day according to your prescription. When the condition begins to improve, you will be able to stop using Metosyn as often, according to the directions given for your condition. If you have been advised to use dressings when you are using this medication, then you should do so. Make sure that you clean the skin before you apply the ointment or the cream, and wash your hands after applying this medicine, unless you are treating your hands.  

Avoid getting this medicine into your mouth, nose or eyes, and rinse thoroughly with water if you get the ingredients into any of these areas. Do not use this medicine for longer than you are advised to do so by a doctor. Metosyn cannot be used with moisturizers and other products as they may dilute the substance. If you are going to use other substances on the same patch of skin, you will need to leave thirty minutes before applying each product.  

What dosages are available? 

The dosage given for Metosyn will be dependent on various factors, including how your body has responded to previous corticosteroids, and the kind of condition you are trying to treat. Metosyn is available in both cream and ointment form, depending on your condition. Usually, this medication will be available in tubes of 25 to 100 grams. You will need to follow your consultant's instructions regarding how long you should be taking the medication for. 

Usually, you will need to apply a thin layer of the cream or ointment directly to the affected area, up to twice  a day. You may not need to use this medication as often as this depending on your condition. As soon as your condition begins to improve, it is important to begin using this medication less frequently. The medicine should only ever be used when advised to do so by a doctor in children.  

What are the side effects of Metosyn? 

Metosyn and other topical medicines are less likely to have severe side effects than their oral medication counterparts, because less of the active substance is absorbed into the blood stream. However, all medications can affect people in different ways, and it’s important to be aware of the possible issues that might occur when you begin using this medication. Remember, just because a side effect is listed here doesn’t mean that you will experience it.  

The most common side effects of Metosyn will usually occur when you first begin using the medication, as your body and skin will be getting used to the new substances. These side effects often include skin irritation, itching, rashes, or burning at the application sites. Do not continue to use the medication if you think that you might be having an allergic reaction to Metosyn. This allergic reaction could present in the form of a rash, or in swelling around the tongue and throat. See a doctor immediately if you feel dizzy or have trouble breathing after using Metosyn.  

Some more significant side effects of Metosyn might include: 

  • Thinning of the skin; 
  • Reduced pigmentation of the skin; 
  • Excessive or unusual hair growth; 
  • Stretch marks; 
  • Groupings of blood vessels beneath the skin; 
  • Excessive worsening of infections; 

In some cases, prolonged use of medications like Metosyn on broken and raw areas of skin can lead to significant side effects. This often happens when the medication is absorbed through a break or cut into the skin into the blood stream and the body. If you absorb too much Metosyn then this could have an impact on other parts of your body, including an inability to produce the right amount of hormones. Make sure that you speak to your doctor if you need to take Metosyn for an extended period of time.  

When shouldn't you use Metosyn? 

Metosyn is well tolerated by many people. However, it is important to answer any questions that your consultant has about your medical history and condition before you begin using this substance. Some people will not respond well to Metosyn. For instance, this medication should not be used in children unless it is absolutely necessary. Additionally, it is important to use this substance in caution with anyone who has psoriasis. If you are taking Metosyn for psoriasis then you will need to arrange regular checkups with your doctor to ensure that you do not make the condition worse by using excessive amounts of the medication over the long term.  

Metosyn is not intended for people with bacterial skin infections, viral skin infections, or fungal skin infections. You will not be able to use Metosyn to treat acne, or chronic inflammation of the skin. Metosyn is not suitable for an inflammatory rash around the genitals, back passage or mouth, and it cannot be used for nappy rash. This medicine should never be used by individuals who have any allergic tendencies with the active ingredients in the substance, or similar corticosteroids.  

It is important to inform your consultant if you have any allergies, as this medicine can include inactive ingredients that could also cause allergic reactions. Metosyn is not recommended for use during pregnancy unless it is absolutely necessary. If this medication is prescribed during pregnancy then do not use it on large patches of skin. Speak to your doctor if you need any further information. Do not use this medication during breastfeeding or nursing unless your doctor or consultant tells you that it is safe to do so. Metosyn should not be used for long periods of time or on large areas of skin by nursing women.  

Does Metosyn interact with any other medications? 

Medical interactions can occur between all kinds of medicines, including topical substances like Metosyn. It is important that you speak to your consultant about any other substances that you may be using with Metosyn, including any over the counter medications, prescription medications, or herbal supplements. Tell your doctor before you begin taking any different amounts of any medication when using Metosyn at the same time.  

If you are going to use other medications or substances on the same area of skin that you use Metosyn on, then you will need to leave several minutes before you apply each product. This will allow the product more time to be absorbed into the skin to avoid mixing. Follow any instructions given by your consultant or the patient leaflet when using this medication with moisturizers, cosmetics, or any other substances.  

Avoid washing the skin or getting it wet after applying this medication for a period of at least 30 minutes.   

Where can you buy Metosyn? 

Metosyn is available to purchase from collaborating pharmacies after a consultation with one of our EU professionals. Make sure that you answer all the questions asked by your consultant truthfully to ensure this medication is right for you.  

Can you get Metosyn without a prescription?  

At this time it is not possible to get Metosyn without a prescription or consultation. You will need to speak to a professional about your condition before you obtain this medication from a corresponding pharmacy.  


BNF Nice, online, 2019 “Fluocinonide” [Accessed 20th of November 2019] Available on:, online, 2019, “Metosyn ointment”[Accessed 20th of November 2019] Available on: online, 2019 “Fluocinonide for severe inflammatory skin conditions” [Accessed 20th of November 2019] Available on:


Assessed by:

Dr Imran Malik, General practitioner
Registration number: GMC: 4741365

Dr Imran Malik studied undergraduate medicine at King's College University in Central London and clinical studies at the prestigious King's College Hospital. He graduated with a MBBS degree in 2000 and went on to gain postgraduate memberships with the Royal Society of Medicine and also General Practice in 2006.