Naprosyn (naproxen)

Naprosyn (naproxen)

Naprosyn is an anti-inflammatory pain killer, or a non-steroidal anti-inflammatory drug (NSAID). This kind of medication includes the active ingredient Naproxen, which can be used to treat a range of painful conditions, including period pain, arthritis, and gout. More information

A doctor will review your order and write you a prescription, if appropriate. This prescription is then forwarded to a pharmacy. The pharmacy will have your medicine delivered to you within one to three working days. Read more about this process here.

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Naprosyn, otherwise known as Naproxen, is a form of NSAID, or anti-inflammatory medication used for managing pain. This substance slows the production of a substance in your body called prostaglandins, which can act to tell your brain when it should feel pain. Naprosyn can also reduce instances of fever, redness and swelling.  

What is Naprosyn? 

Naprosyn is an anti-inflammatory pain killer, or a non-steroidal anti-inflammatory drug (NSAID). This kind of medication includes the active ingredient Naproxen, which can be used to treat a range of painful conditions, including period pain, arthritis, and gout. Anti-inflammatory medications like Naprosyn work by preventing some of the chemical reactions in your body that cause and worsen inflammation.  

For instance, Naprosyn can reduce the effect of chemicals in the body known as COX enzymes, or cyclo-oxygenase enzymes. These substances work by helping to create other chemicals in the body known as prostaglandins. Often, prostaglandins are produced at the site of an injury and cause both inflammation and pains. By reducing the number of COX enzymes produced, Naprosyn can also reduce the number of prostaglandins in your body, which eases inflammation and pain.  

Naprosyn is a prescription-only pain killer that is intended for short-term use only. In some cases, this medication might be used with other substances to provide a complete treatment plan.  

When is Naprosyn used? 

Naprosyn is a substance that can relieve the pain from various conditions, including headaches and migraines, muscle pains, dental pain, tendonitis, menstrual cramps, and even acute injuries. In some cases, doctors will also prescribe Naprosyn to help with managing the inflammation, joint stiffness and pain caused by attacks of gout, bursitis and arthritis.  

NSAIDs like Naprosyn reduce the production of the natural substances that cause inflammation in the body, so it’s easier to manage chronic and acute conditions. If you are treating a condition like arthritis, you can ask your doctor about other medications and non-drug treatments that will help with your pain too.  

Naprosyn could be used alongside a rehabilitation or physiotherapy treatment designed to give people more movement after an injury or surgery.  

How do you use Naprosyn? 

It is important to pay close attention to the instructions provided by your consultant when you get Naprosyn. Your medication will come with a patient leaflet that includes all of the information that you might need to use about how to use these pills, and how they work. Reading the patient leaflet will provide you with the guidance you need to use this drug correctly.  

Naprosyn is well-tolerated form of pain medication, but you will need to ensure that you are using it correctly to get the best results. Usually, Naprosyn is only intended for short-term treatment of pain issues, and it should not be used long-term without the guidance of a doctor.  

Naprosyn pills can be taken by mouth as directed by a doctor or patient leaflet. Often, you will be able to take Naprosyn up to three times each day with a glass of water. Do not lie down for 10 minutes after you take this drug as that could cause an increased risk of side effects. If you’re concerned that taking Naprosyn may cause an upset stomach, you can take the drug with a piece of food or milk. Naprosyn is safe to take with antacids.  

If you are taking Naprosyn on an as-needed basis rather than on a regular schedule, remember that medications like this one will often work best if they’re used when the first signs of pain begin to develop. If you wait until the pain has worsened before you seek help, then your medication might not work as well.  

What dosages are there? 

Naprosyn dosages will be based on a number of things, including your current medical condition and the issue that you are trying to treat. Usually, your doctor or consultant will attempt to reduce your risk of experiencing side effects with this medication by starting you on a low dose and gradually increasing that dose over time. Do not increase the dose of Naprosyn that you have been given without seeking approval from a doctor first.  

For ongoing conditions, make sure that it is safe to take this pill on a regular basis. Your doctor may need to move you to a different medication if Naprosyn doesn’t appear to be having the desired effect on your pain and inflammation.  

The usual dose of Naprosyn is 1-2 tablets taken twice a day after food. Usually, this pill will come in a packet of 56 tablets, with each tablet containing 250mg of naproxen.  

What are the side effects of Naprosyn? 

Along with their intended effects, many drugs like Naprosyn can also come with side effects that may impact different people in different ways. Sometimes, the side effects that are most common with Naprosyn may only happen when you first begin to take the medication. Once your body gets used to the new ingredients, these side effects could go away on their own. 

The most common side effects associated with Naprosyn include headaches, drowsiness, and dizziness. Some people also experience upset stomachs, nausea, heartburn, and general feelings of unwellness. If any of these conditions persist, speak to a doctor.  

In certain cases, using Naprosyn regularly can raise your blood pressure. Your doctor may request for you to check your blood pressure regularly and find out whether the results are higher than they should be. Speak to your doctor immediately if you have any more severe side effects, include: 

Easy bleeding or bruising; 

  • Pain with swallowing or difficulty swallowing or  Heartburn 
  • Changes in your hearing; 
  • Changes in your mood; 
  • Signs of kidney problems, like changes in your amount of urine; 
  • Stiff neck you can’t explain; 
  • Vision changes; 
  • Signs of heart failure, like swelling ankles. 

In very rare circumstances, this medication can cause fatal liver disease issues. If you notice any signs of liver damage, including vomiting and nausea that doesn’t stop, loss of appetite, stomach and abdominal pain, dark urine, yellowing eyes, or changes to skin tone, contact a doctor. A very serious reaction to this drug is rare. However, you should seek medical help immediately if you notice signs of an allergy, such as trouble breathing, a rash, itching, or swelling in the throat, face or tongue.  

When shouldn't you use Naprosyn? 

Naprosyn may not be a suitable treatment for everyone with pain issues. Before you take Naprosyn or any other medication including Naproxen, tell your consultant if you are allergic to it, or any similar NSAIDs like ibuprofen. If you have any other allergies, tell your consultant about those too, as Naprosyn might include inactive ingredients that also cause responses.  

Before you use this medication, tell your consultant about your medical history with things like aspirin-sensitive asthma, or blood disorders like problems with your clotting abilities. You should also make sure that your doctor is aware of any heart disease issues that you have had in the past, issues with high blood pressure, liver disease, or stroke.  

You should not take this medication is you have ever suffered with gastric ulcers, gastritis or suffer with regular heartburn. 

Regular use of NSAID medications can sometimes lead to kidney problems. This can be the case when you are using Naprosyn. Problems are more likely to happen if you are suffering from dehydration, or you have had kidney disease in the past. You may also have a higher risk of dangerous side effects if you are an older adult.  

In some cases, Naprosyn can cause you to feel drowsy or dizzy. Alcohol can worsen these effects, so do not use machinery or drive until you’re sure that you’re comfortable to do so. In rare cases, Naprosyn can cause stomach bleeding. Certain things can increase your chances of this side effect, including regular use of tobacco and alcohol. Make sure that you limit your exposure to alcohol as much as possible.  

Naprosyn and similar medications can make some people more sensitive to sunlight. To avoid burns and skin damage, limit the time that you spend in the sun and avoid tanning booths or sunlamps. Use protective clothing when you’re outdoors and speak to a doctor if you experience any burns. 

Does Naprosyn interact with any other medications? 

When answering the questions provided by your consultant, it’s important to ensure that you provide a complete list of medications that you are already using before you take Naprosyn. These medications may include over the counter drugs, as well as medicines that have bene prescribed to you by a doctor or consultant in the past. Make sure you mention any herbal supplements too.  

Naprosyn can interact with medications and increase your chances of side effects. For instance, it’s not a good idea to take Naprosyn with ACE inhibitors, or angiotensin II receptor blockers. You should also avoid using Naprosyn at the same time as corticosteroids, lithium, or pills that are known as diuretics or water pills.  

In some cases, Naprosyn can have a higher risk of stomach bleeding when it is taken with other medications that might cause bleeding, such as clopidogrel, or blood-thinners like warfarin.  

Avoid using more than one   NSAIDs together. Your doctor and consultant will often recommend avoiding drugs like ibuprofen and aspirin when you are taking Naprosyn. These substances contain similar drugs to naproxen and will therefore increase your risk of side effects. If you are taking aspirin to reduce your risk of a stroke or heart attack, ask your doctor whether you should continue your treatment. Many other medication also interact with naproxen, your doctor will check to make sure this is safe for you. 

Where can you buy Naprosyn? 

Naprosyn is available to buy from A consultant will discuss your case with you and write a prescription that can be forwarded to a pharmacy near you. Your medicine can be delivered within 3 working days.  

Can you get Naprosyn without a prescription?  

It is not possible to get Naprosyn without a prescription. You will need to speak to a consultant before getting this medication.  

Sources, online, 2019, “Naprosyn” [Accessed 3rd of December 2019], Available on:: 

Health Direct,  online, 2019, “Brand name: Naprosyn”, [Accessed 3rd of December 2019], Available on:,15611000168108/naprosyn 

RXList online, 2019,  “NAPROSYN” [Accessed 3rd of December 2019], Available on: 

Assessed by:

Dr Imran Malik, General practitioner
Registration number: GMC: 4741365

Dr Imran Malik studied undergraduate medicine at King's College University in Central London and clinical studies at the prestigious King's College Hospital. He graduated with a MBBS degree in 2000 and went on to gain postgraduate memberships with the Royal Society of Medicine and also General Practice in 2006.