Onbrez is a form of inhaler that uses the active ingredient indacaterol to tackle issues like COPD. Indacaterol is a medicine that belongs to a group of drugs called long-acting beta agonists. More information

A doctor will review your order and write you a prescription, if appropriate. This prescription is then forwarded to a pharmacy. The pharmacy will have your medicine delivered to you within one to three working days. Read more about this process here.

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Patient Leaflet(s)

Onbrez is a form of inhaler-based treatment that contains the active substance indacaterol. This medication helps to treat conditions where breathing might be limited or damaged, such as COPD. This medication can last for up to 24 hours.

What is Onbrez? 

Onbrez is a form of inhaler that uses the active ingredient indacaterol to tackle issues like COPD. Indacaterol is a medicine that belongs to a group of drugs called long-acting beta agonists. Onbrez works on the receptors in the lungs known as beta receptors. By stimulating these receptors, the substance can cause the muscles in your airways to relax, allowing you to breathe more easily.  

In conditions where the airways narrows, such as COPD or chronic obstructive pulmonary disease, it's difficult for air to exit and enter the lungs normally. However, by opening the airways, Onbrez can make it much easier for you to breathe.  

Onbrez doesn't open the airways as quickly as short-acting agonists like terbutaline or salbutamol. Instead, it's intended for long-term use, when you want to make sure that the airways can stay open for periods of at least 24 hours. On the other hand, substances like terbutaline only act for up to 5 hours. Onbrez is taken using a breezhaler - by inhaling the medication directly into the lungs, you can ensure that you get the biggest impact from the drug as quickly as possible. This often means that you won't absorb as much of the medication in Onbrez into your blood as you would if you were to take it in tablet form, too.

When is Onbrez used? 

Onbrez is a type of bronchodilator that widens the airways and relaxes the muscles around your airways so that you can breathe more naturally. Your doctor will prescribe this medication to help eliminate the side effects and symptoms associated with COPD (Chronic obstructive pulmonary disease), such as trouble breathing or wheezing.  

Unlike other inhalers for COPD, Onbrez needs to be used on a regular basis, often every day. When used regularly, this long-acting medication will stop you from encountering as many attacks of breathlessness as you might have without medication. Onbrez is not a rescue treatment if you're suffering from sudden loss of air. Onbrez should not be prescribed as a solution for anxiety attacks, as it doesn't address the breathing problem instantly.  

Onbrez may be combined with other forms of medication, including rescue inhalers, to provide a more comprehensive treatment strategy for people with COPD. 

How do you use Onbrez? 

It's crucial to use your breezhaler properly when you're given Onbrez. If you're not sure about how to use an inhaler, ask your doctor to demonstrate for you before you begin using Onbrez. You will also be able to follow the instructions that are provided on the patient leaflet inside the medication package. If you have any questions, contact your doctor or pharmacist.  

The inhaler created for Onbrez is intended to be very easy to use. To begin, make sure that the inhaler is clean, and remove the cap. Hold the base of your device and tilt the mouthpiece upwards to open the inhaler, ready to take your medication. You will need to remove a capsule from the blister packet included with your inhaler and put it into the chamber of the inhaler. When you close the device, you will hear a click. This indicates that you're ready to pierce the capsule.  

Hold the inhaler as normal and press both of the buttons on each side of the device at the same time, you will hear the capsule being pierced. Release the side buttons, and exhale away from the inhaler. Once you have emptied your lungs, place your lips around the mouthpiece, and close your mouth firmly around it. Breath in normally and hold your breath for around 5 to 10 seconds at the top of your inhalation. You can then breathe out as usual.  

Remove the empty capsule from the inhaler and replace the cap. Make sure that you use your inhaler at the same time every day as possible. This will help you to remember to use your medication regularly. If you forget to use the inhaler, take it as soon as you remember. If you don't remember to use your Onbrez until the next day, skip the missed dose.  

What dosages are available? 

Onbrez is available in a range of different doses depending on your needs. The most common strength for the capsules is either 150mg or 300mg. Your doctor may start by giving you the 150mg capsule, before moving you up to the 300mg if they feel you need a stronger treatment. This will give them a chance to see whether you tolerate the medication well.  

Unless your doctor advises otherwise, the typical dose of Onbrez for most people is one capsule inhaled once per day, at the same time each day. It is not a good idea to use this substance if you are under the age of 18. Do not swallow the capsules included with the inhaler.  

What are the side effects of Onbrez? 

Most people will be able to tolerate Onbrez very well, without any serious side effects. However, medication can affect different people in different ways. It's worth being aware of the side effects that medications like Onbrez can cause. Remember, you may experience symptoms that are not listed below. If you have any reactions to Onbrez that make you uncomfortable, contact your doctor or pharmacist to find out whether you should continue using the medication.  

The most common side effects of Onbrez include: 

  • Dizziness  
  • Headache 
  • Increased risk of respiratory tract infections 
  • Sinus inflammation 
  • Sore throat 
  • Blocked or runny nose 
  • Chest pain 
  • Muscle spasms 
  • Swelling of the ankles and legs caused by fluid retention 

Tell your doctor if you experience any persistent chest pain when taking Onbrez. It is particularly important to seek advice if you become overly aware of your heartbeat or feel that your heart is beating faster than normal, or more slowly than normal. Speak to a doctor if you have pins and needles anywhere in your body, itching, rashes, or pains in your muscles or bones.  

Please read the medication leaflet in full to get a complete overview of the other side effects that may be associated with Onbrez treatment. Although an allergic reaction to this substance is rare, seek emergency attention from a medical professional if you have sudden trouble breathing after using Onbrez or you notice swelling in your throat, mouth or lips.  

If you think that you have experienced a side effect from Onbrez that isn't listed here, contact your doctor or pharmacist for advice.  

When shouldn't you use Onbrez? 

Onbrez will not be the best treatment option for everyone with COPD. There are many forms of treatment available for this condition, and your doctor will be able to suggest an alternative if this isn't right for you.  

In rare cases, Onbrez may increase blood sugar levels in people with diabetes, your doctor might ask you to monitor your conditions more carefully when you're using this medication. Additionally, it's important to use this medication with caution if you have had, or currently have: 

  • Heart disease or heart problems 
  • Abnormal heart rhythms 
  • Unusually high blood pressure 
  • Epilepsy 
  • Low levels of blood potassium 
  • An overactive thyroid gland 
  • Severe liver disease 

Onbrez should not be used by anyone who suffers from asthma - a different form of treatment will be necessary. It is not appropriate to use this medication if you are breastfeeding, as the substance might pass through into your breast milk. Onbrez should not be given to children and adolescents younger than 18 years of age. You may not be able to take this medication if you're allergic to any of its ingredients. Onbrez often includes lactose, which means that it isn't suitable for people with a lactose intolerance. 

Does Onbrez interact with any other medications? 

Medications can sometimes interact negatively with other substances that you might be using to manage your condition. It's important to tell your doctor what medicines you're already taking, including any that you have already bought with a prescription, medications that you have accessed over the counter, and herbal substances or supplements.  

This inhaler should not be used with other medications that include long-acting beta-agonists, such as formoterol, or salmeterol. Additionally, this substance should not be used in combination with medications that are used as beta-blockers, such as propranolol. Onbrez has an opposite effect to these medications and may cause the airways to narrow.  

In some circumstances, Onbrez can potentially cause a decrease in the levels of potassium in the blood, which can also lead to adverse effects on your health. It's important not to take this substance with other medications that might also lower your potassium levels.  

Where can you buy Onbrez? 

Onbrez is available to purchase from your own pharmacy, or you can arrange for us to deliver this medication to a registered pharmacy on your behalf. Make sure that you speak to a doctor before using this substance. We can arrange for a consultation with a doctor for you.  

Can you get Onbrez without a prescription?  

As with most treatments for COPD, it is not possible to purchase Onbrez without a prescription from your doctor. A doctor will need to assess your condition carefully and look at your medical history to ensure that the treatment is right for you.  



Drugs.com, 2019, online, Onbrez inhaler [Accessed on the 27th of August 2019], Available at: https://www.drugs.com/uk/onbrez-breezhaler.html

Michael Steward, Sid Dajani, 2018, online, Indacaterol for COPD [Accessed on the 27th of August 2019], Available at: https://patient.info/medicine/indacaterol-for-copd-onbrez-breezhaler 

Mims.com, 2019, online, Onbrez inhaler [Accessed on the 27th of August 2019], Available at: https://www.mims.co.uk/drugs/respiratory-system/asthma-copd/onbrez-breezhaler