Anoheal cream relieves pain in the anal region caused by fissures or tears. It contains the active ingredient diltiazem, which is a so-called ‘calcium blocker’. Anoheal cream is a prescription-only medicine that can be ordered online through a partner pharmacy.

What is this medicine used for?

Anoheal cream is used for relieving pain due to anal fissures, which are cracks or tears in the lining of the anus and anal canal. These are caused by trauma to the anus, with the most commonly associated causes being chronic constipation, excessive straining during bowel movement and anal sex. Anal fissures cause problems such as itching and pain, especially after a bowel movement, and in some cases blood in the stool. Anoheal cream dilates blood vessels, which improves blood supply to the anus and helps the fissure to heal. Anoheal cream also relaxes the anal muscles, which reduces the anal fissure pain.

How to use Anoheal cream

Cleanse the anus with a cotton ball dipped in water or oil. Anoheal cream is then applied inside and around the anus using your finger. Wash your hands after applying the cream. It may take some time before the effect of Anoheal cream is noticed, and you should keep using it for as long as your doctor has prescribed. In most cases, it takes two weeks for the medicine to reach full effect and the anal fissure pain to subside. Although the pain may go away, it may take several weeks or months for the fissure to heal completely. An important part of the treatment for anal fissures also involves trying to prevent constipation. You should therefore drink at least two litres of water a day, choose foods that are high in fibre and exercise on a regular basis. You should also not delay going to the toilet when you feel the need.


Unless otherwise prescribed by a doctor, you should apply a strip of Anoheal cream about two cm long to the affected area twice daily (morning and evening). Read the package leaflet before use.

Side effects

As is the case with all medicines, Anoheal cream may cause side effects. The ones known to be associated with this medicine are irritation (an itching or burning sensation) at the application site, headaches and dizziness. Most side effects will disappear when use is discontinued. Consult a doctor if the side effects are severe or if you experience ones that are not listed on the leaflet.

When not to use Anoheal cream

Do not use Anoheal cream if you are allergic to the active ingredient diltiazem or any other ingredient in this medicine. Check the package leaflet for a list of ingredients.

Pregnancy/driving ability/alcohol

Do not use Anoheal cream if you are pregnant, planning to conceive or breastfeeding, unless otherwise advised by your doctor. Anoheal cream does not affect your ability to drive safely. However, alcohol can intensify the side effects of Anoheal cream. It is therefore advisable to reduce or stop alcohol consumption while taking this medicine.

Patient Leaflet(s)
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