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Clinorette

Clinorette is a medicine that is used to provide relief from the symptoms of menopause. It is a hormone replacement therapy (HRT) preparation that is given as a supplement to replace falling hormone levels in the body. The active ingredients estradiol and norethisterone restore hormonal balance, which helps reduce symptoms in women going through menopause. Clinorette is a prescription-only medicine.

What is Clinorette?

Clinorette is a medicine that is used to provide relief from the symptoms of menopause. It is a hormone replacement therapy (HRT) preparation that is given as a supplement to replace the falling hormone levels in the body. The active ingredients estradiol and norethisterone restore hormonal balance, which helps reduce symptoms in women going through menopause. Clinorette is a prescription-only medicine.

What is Clinorette used for?

As women age, hormone production in the body decreases. This can cause different types of pre- and post-menopausal symptoms, including:

  • Irregular periods;
  • Hot flushes;
  • Night sweats;
  • Dryness of the eyes and/or mouth;
  • Anxiety, mood swings or depression;
  • Sleep problems;
  • Loss of libido;
  • Painful sex due to vaginal dryness;
  • Osteoporosis (decrease in bone mass and density).

Clinorette HRT is used to treat women who have not had a hysterectomy. The oestrogen in Clinorette (in this case in the form of estradiol) helps reduce distressing menopausal symptoms. Clinorette HRT also contains a progestogen hormone, norethisterone, which opposes oestrogen’s effect on the womb lining to prevent the risk of serious side effects.

How to use Clinorette

Clinorette HRT comes in blister packs of 28 tablets. The white tablets taken in the first 16 days of each Clinorette HRT cycle contain only estradiol, while the pink tablets that are taken in the last 12 days of each cycle contain both estradiol and norethisterone. The tablets should be taken at the same time each day with some water, and can be taken with or without food. Clinorette HRT tablets should be taken back-to-back without a tablet-free interval. During the fourth week of your cycle, you will have a monthly withdrawal bleed. If Clinorette HRT is used for more than two years, its use should be reviewed by a doctor.

Dosage

Unless otherwise advised by a doctor, the usual dose in adult women is one tablet a day. Do not exceed the recommended dose and read the package leaflet carefully before use.

Side effects

HRT can cause side effects. The following are some of the side effects that are known to be associated with Clinorette HRT:

  • Headaches;
  • Nausea, stomach-ache or other gastrointestinal symptoms;
  • Breakthrough bleeding (spotting);
  • Vaginal discharge;
  • Breast tenderness or soreness;
  • Mood swings.

Most side effects are temporary and mild, but you should consult a doctor if they become severe or persistent. Read the package leaflet thoroughly before use. It is important to be aware that all women using HRT have a slightly increased risk of serious side effects such as breast cancer and thrombosis compared with women who do not use HRT. See the package leaflet for further information.

When not to use Clinorette

Clinorette is not suitable for everyone. Do not use this HRT preparation if you:

  • Are allergic to estradiol, norethisterone or any other ingredient in this medicine;
  • Have a known or past history of thrombosis, liver disease, breast cancer or other hormone-related cancer;
  • Have vaginal bleeding of unknown cause or an overgrowth of the lining of the womb (endometrial hyperplasia);
  • Have a blood disease or severe kidney disorder.

Consult a doctor on the use of Clinorette HRT if you have a health condition that is not listed above or are currently on medication.

Pregnancy/driving ability/alcohol

Do not use Clinorette if you are pregnant or breastfeeding, unless otherwise advised by your doctor. Warning: Clinorette HRT is not a contraceptive pill! If you are still capable of becoming pregnant, you should use contraception as a precaution. This medicine does not interact with alcohol or affect your ability to drive safely.

Patient Leaflet(s)
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