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Mirvaso gel is a form of prescription medication designed to treat conditions like persistent skin redness and rosacea. Mirvaso gel contains an active ingredient called brimonidine, which is an alpha antagonist.

What is Mirvaso?

Mirvaso is a form of topical brimonidine gel that is available on prescription. It should only be applied directly to the skin and is not designed to be taken orally. Mirvaso gel contains the active ingredient brimonidine, which is a medication often used for the treatment of flushing and redness in the skin.

Mirvaso is an opaque gel that can be white or yellow in color. In some cases, brimonidine gel will be given with other treatments as part of a full medical strategy. Often, Mirvaso works by helping to reducing symptoms like redness and discomfort in the skin. The active ingredient in Mirvaso, brimonidine causes the blood vessels in the skin to narrow, which reduces inflammation.

Mirvaso gel can pass through the various layers of epidermis in the skin to work directly on the blood vessels. Usually, each gram of treatment with Mirvaso gel will include around 3.3 mg of Brimonidine, as well as some other inactive ingredients.

When is Mirvaso used?

Mirvaso is a topical medication only available on prescription. Usually, brimonidine gel is used for the treatment of a common skin disorder called rosacea, or adult acne. This issue can sometimes cause the blood vessels in the skin to become enlarged, leading to the presence of redness, flushing, and blemishes.

Mirvaso helps to reduce these symptoms by narrowing the blood vessels in the skin. However, Mirvaso gel rosacea is not an acute treatment for the symptoms of rosacea, but instead, doctors and consultants prescribe this medication to be used on a daily basis to reduce the risk of rosacea taking place.

Mirvaso must be applied according to the instructions given by a doctor or medical professional. It is not safe to use this medication without a prescription.

How do you use Mirvaso?

You should always read the patient leaflet that comes with your medication when using a new treatment or getting a repeat dose of a treatment that you have used before. When you are prescribed Mirvaso brimonidine, you should also follow the instructions provided by the person prescribing the medication.

Mirvaso is intended for topical use only. Avoid getting the medication into your mouth, eyes, or on your lips. If you get the medication on any of these areas, or onto any broken skin, then rinse the area thoroughly with warm water.

Wash your hands before and after applying Mirvaso, and make sure that the area to be treated is clean before the application begins. When you’re ready, take a pea sized amount of brimonidine gel and place it evenly across the areas that need treatment, such as the nose, chin, and forehead. Gently spread the Mirvaso gel across the area, following the directions given to you.

Make sure that you allow around fifteen minutes at least before you apply any other creams, moisturisers or cosmetic products after using Mirvaso. This will help to ensure that the brimonidine gel has properly soaked into your skin.

What dosages are there?

Mirvaso gel comes in a tube with a 0.33% strength of Brimonidine. This medication should be applied regularly for you to get the best benefit from it. Your doctor or consultant will usually recommend applying Mirvaso gel at least once a day. Follow the instructions given to you carefully.

Mirvaso is usually applied topically to an affected area for a period of at least thirty days. However, this medication should not be used by children under the age of 18 unless you are told otherwise by a doctor.

Do not apply more of the Mirvaso gel than your doctor tells you, applying extra gel to your skin will not cause your symptoms to disappear more quickly, but it could increase your risk of side effects. If you feel as though you are not getting any benefit from this medication after a couple of weeks of using it, tell a doctor.

To keep your risk of possible side effects as low as possible, your doctor may advise you to use a smaller amount of medication at first and increase your dose gradually. Follow the instructions provided by your doctor carefully.

What are the side effects of Mirvaso?

Mirvaso brimonidine and similar topical treatments can cause side effects. Usually, the side effects associated with topical treatments are very small, because only a small amount of the active ingredient in the medication will be absorbed into your blood stream. However, it is important to be aware of the possible side effects that might occur when using any medication, so you know how to respond safely.

Flushing and burning of the skin can occur in some cases when you first apply Mirvaso. This might happen when your skin is first getting used to the Mirvaso brimonidine, and the symptoms should disappear after a short time. Remember that you have been given this medication because the benefits to you are deemed to be greater than the possible side effects.

Most people taking Mirvaso will not have any significant side effects. However, it is possible for side effects to occur in some cases. Tell your doctor immediately if you have any side effects such as a slow heartbeat, fainting, dizziness, whitening skin, or paleness.

Other possible side effects may include:

  • Swelling on the face;
  • Dry mouth;
  • Acne;
  • Worsening rosacea;
  • Skin rashes;
  • Cold feet and hands;
  • Nausea;
  • Nasal congestion;
  • Headaches.

If any of those symptoms occur, you should seek medical attention immediately, and stop using Mirvaso until you know that it is safe to continue with your treatment.

A very severe allergic reaction to Mirvaso is rare. However, it is important to seek medical attention immediately if you notice any signs that might indicate an allergic reaction. For instance, in some cases, allergic reactions might cause symptoms like swelling in the lips or tongue, or rashes. Make sure that you seek help if you have trouble breathing.

This is not a complete list of the possible side effects that could happen when using Mirvaso. If you encounter side effects that are not listed here, then seek guidance from a doctor.

When shouldn’t you use Mirvaso?

Mirvaso might not be a suitable treatment for everyone. Usually, it is recommended for people over the age of eighteen, and should not be used by children under this age unless specifically advised otherwise.

Before you begin using Mirvaso, make sure that your doctor or consultant is aware if you are allergic to this medication or anything else. Brimonidine gel may contain inactive ingredients that can also cause an allergic response. You should speak to your pharmacist if you are concerned.

Before you begin taking Mirvaso, tell your doctor or consultant about your full medical history and answer any questions that they might have. It is important to tell your doctor about:

  • Blood vessel diseases;
  • Blood circulatory disorders;
  • Heart disease;
  • Depression;
  • Low blood pressure;
  • Connective tissue disorders;
  • Immune system disorders.

Avoid triggers that could make your condition worse, such as hot drinks, alcohol, and spicy foods. You could also find that your condition gets worse when you spend time in a hot place. If you go outside, wear plenty of protective clothing and sunscreen to avoid taking on extra damage from the sun.

Before you have any surgeries or treatments, make sure that your doctor or dentist is aware of the products that you use, including any over-the-counter medications, prescription, or non prescription drugs. You should avoid this medication during pregnancy when it is deemed absolutely necessary.

It is not certain at this time if Mirvaso can pass into breast milk. If you are breast feeding then you should not use brimonidine gel, your doctor can advise you further.

Does Mirvaso interact with other medications?

Mirvaso and other medications may sometimes interact negatively, increasing your risk for significant side effects. Before you use Mirvaso gel, it is important to make sure that your doctor or consultant is aware of exactly what you take. This includes any prescription medications, over-the-counter drugs, herbal remedies, or anything else that you use, including recreational drugs.

Make sure that you keep a list of all the medications that you are using at any time. Mirvaso may interact with other skincare products such as moisturisers and abrasive cleansers. With that in mind, ask your doctor what you can use safely. If you are using cosmetics after Mirvaso, make sure that you give at least fifteen minutes for the medication to soak into your skin first. Where can you buy Mirvaso?

Mirvaso brimonidine gel is available to purchase from all offline and online pharmacies in most cases, provided that you have a prescription for this medication. The consultation you have will determine if Mirvaso is right for you.

Can I get Mirvaso without a prescription?

Mirvaso is not available to purchase without a prescription. Do not use Mirvaso unless you have confirmed with a doctor or professional that it is the correct treatment for you. If Mirvaso is not suitable for your needs, then you may be able to take another form of treatment that is safer for you.

Sources, (2019, November) User Reviews for Mirvaso, Retrieved March 14th 2020 from: (2020, February 11) Mirvaso 3mg/g Gel Retrieved March 27th 2020 from:

RXList, (2018, June 03) Mirvaso Side Effects Center Retrieved March 27th 2020 from: effects-drug-center.htm

Patient Leaflet(s)

Reviewed by:

Dr Imran Malik, General practitioner Registrationnumber: GMC: 4741365 Last checked: 17-01-2023 | Still valid

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