Trimovate cream

Trimovate cream

Trimovate cream contains nystatin, oxytetracycline, and clobetasone butyrate. This medication is used for the treatment of inflammatory skin conditions and is only available on prescription within the UK. More information

A doctor will review your order and write you a prescription, if appropriate. This prescription is then forwarded to a pharmacy. The pharmacy will have your medicine delivered to you within one to three working days. Read more about this process here.

Instruction costs (includes consult & service fee)
Service – Instruction costs (includes consult & service fee)

Trimovate cream is a medication used for the treatment of various inflammatory conditions of the skin, including acne. This medication contains three separate active ingredients, including nystatin, oxytetracycline and butyrate.  

What is Trimovate cream? 

Trimovate cream contains nystatin, oxytetracycline, and clobetasone butyrate. This medication is used for the treatment of inflammatory skin conditions and is only available on prescription within the UK. There currently aren’t any other medications available in the UK that contain the same substances.  

The different ingredients in Trimovate cream work in unique ways. For instance, Clobetasone butyrate is a form of medication known as a topical corticosteroid. This substance works on the cells of the skin to prevent them from releasing inflammatory substances. By doing this, Trimovate cream can help to reduce symptoms of itching, redness, and swelling. Clobetasone is a type of moderate-strength steroid.  

Trimovate cream also contains oxytetracycline, which is a medication used for the treatment of infections and bacteria. This substance works by stopping bacteria from producing the proteins essential for their growth. Without the correct proteins, the bacteria on the skin cannot grow and replicate.  

Finally, Nystatin is an antifungal medication in Trimovate cream that kills yeast and fungi by damaging the cell membranes that allow them to remain strong. The combination of all three ingredients in Trimovate cream can be ideal for treating areas of moist and inflamed skin. On the other hand, an ointment may be prescribed for dry skin.  

When is Trimovate cream used? 

Trimovate cream is used for the treatment of various inflammatory skin conditions that may also be infected with fungi or bacteria. This may include conditions like nappy rash, dermatitis, eczema, and inflammation caused by friction between different patches of skin.  

Trimovate cream is only available on prescription in the UK and should not be given for longer than 7 days. You should not use this medication for longer than your doctor or consultant advises you to do so. Trimovate cream can be used for the treatment of acne, particularly when the spots become infected on the skin. Remember, stopping using Trimovate cream before your doctor tells you to could mean that you become resistant to the antibiotic. It could also mean that your condition returns or worsens.  

How do you use Trimovate cream? 

Whenever you start using a new medication, it is important to follow the guidance given by your consultant or doctor carefully, to ensure that you are using it correctly. When using Trimovate cream, you should follow your doctor’s instructions, but also read the instructions provided for you on the patient leaflet included with the medication.  

Trimovate cream should not be diluted with any other ointments or creams when applied to your skin. Additionally, you should not cover the treated area with any dressings that might prevent the air from getting to the skin. Dressings can increase the absorption of the steroidal ingredients in Trimovate cream which might increase your risk of side effects.  

Do not apply the skin to any broken skin or open wounds and avoid using it on skin that has been affected by viral or bacterial skin infections, such as chickenpox, or impetigo. Do not use Trimovate cream with fungal skin infections, or acne without the guidance of your doctor. Trimovate cream should not be used on itching without an evaluation, or infections with certain kinds of bacteria.  

Before using Trimovate cream, make sure that you clean the skin that you will be applying the medication to, and wash your hands. Apply a thin layer of this medication to the skin, taking care to avoid the eyes, mouth and nose. Do not use Trimovate cream for long periods without the approval of your doctor. If your symptoms do not improve after a week, speak to a doctor.  

What dosages are there? 

Your consultant or doctor will guide you on how much of this medication to use for your condition. Usually, the typical dosage will be a thin layer of medication applied directly to the affected skin once or twice per day. You will be advised on how long you will need to continue using Trimovate cream. Like other antibiotics, it is important that you finish the prescribed course to ensure that the infection is completely cleared from your system.  

Trimovate cream should not be taken for extended periods of time because of the steroid ingredient within it. Additionally, you should not apply this medication to large areas of skin. You will need to use this medication regularly to see the correct results. If you forget to use your cream at the right time, use it as soon as you remember. However, do not apply a heavier dose of the cream than usual to make up for a missed dose. Using more Trimovate cream than necessary will not improve your condition any faster, but it will mean that you are more susceptible to Trimovate cream.  

Wash your hands after using Trimovate cream, unless your hands are the areas in need of treatment.  

What are the side effects of Trimovate cream? 

Trimovate cream, like many other medications, can sometimes cause unintended side effects. The way that people respond to Trimovate cream will differ depending on their medial background and genetic makeup. Although this medication is very well tolerated, it is possible that you will still experience side effects. Making sure that you are aware of the side effects of Trimovate cream will help you to determine when you should seek medical help. 

Because Trimovate cream is applied as a topical solution to the skin, it is unlikely that you will absorb enough of the steroid and other ingredients into your bloodstream to have any serious side effects. However, you may notice some mild side effects, particularly when you first begin using Trimovate cream. These might include slight irritation at the application site where you use the cream, including burning and itching.  

Some people may also find that their skin is more sensitive to UV rays and sunlight when using Trimovate cream. If this is what happens to you, then you should be careful when exposing your skin to sunlight during Trimovate cream treatment.  

If you excessively apply Trimovate cream to your skin several times a day or for longer periods of time than necessary, you may notice side effects caused by overexposure to corticosteroids, such as skin thinning or hair growth. These side effects are also more likely when Trimovate cream is applied to broken or thin areas of skin. You can also be more likely to experience side effects when Trimovate cream is used on areas of skin that rub together, as this can cause for a faster absorption of the medication. 

In some rare circumstances, Trimovate cream and the antibiotics within it can cause inflammation in the bowel that leads to severe stomach cramps and diarrhea. It is unlikely that this will happen with topical antibiotics, but you should seek a doctor’s advice if you develop serious diarrhea and stomach cramps. Additionally, although an allergic reaction to this medication is rare, stop using it and seek help if you experience swelling around the lips or tongue, or trouble breathing.  

When shouldn’t you use Trimovate cream? 

Trimovate cream may not be suitable for all people, particularly if you have certain conditions. You will need to answer the questions asked by your consultant carefully to ensure that this treatment is appropriate for you. For instance, if you have reacted poorly to corticosteroid creams in the past or you have an allergy to any of the active or inactive substances in Trimovate cream, do not use it.  

Make sure that you inform your consultant about any history of issues that you have with skin conditions and note that Trimovate cream may not be recommended for use in people who are pregnant or breastfeeding. Although it is unlikely that this medication will be absorbed into the blood enough to affect a child, you should seek advice from your doctor.  

You should not use this medication on children, and it is important to seek additional advice if you have skin infections caused by certain forms of bacteria. If Trimovate cream is not suitable for you, then your consultant may be able to suggest another treatment.  

Does Trimovate cream interact with other medications? 

Before taking Trimovate cream¸ make sure that your consultant is aware of whether you are taking any other medications. Substances including over the counter medications and prescription drugs may not be suitable to take with Trimovate cream. It is particularly important to be cautious if you are using Trimovate cream with other corticosteroid medications.  

If you need to use other medications on the same skin where you are applying Trimovate cream, make sure that you leave plenty of time between each application to avoid mixing the substances on your skin. If you are going to use a moisturizer with Trimovate cream, then use it thirty minutes before applying Trimovate cream. This will soften your skin and may help Trimovate cream to be absorbed into the skin.  

Where can you buy Trimovate cream? 

If your doctor has advised using Trimovate cream, it is available to purchase safely online following a consultation with a professional.  Once you have completed your consultation, your consultant will be able to provide you with a prescription sent to a local pharmacy on your behalf.  

Can I get Trimovate cream without a prescription? 

Trimovate cream is not available without a prescription in the UK. If your consultant agrees that you need this medication, you will be able to collect it from a pharmacy within 3 working days.  

Sources 2020, “TRIMOVATE CREAM” [Accessed 8th of January 2020], Available on:, “ Trimovate available to prescribe again”  [Accessed 8th of January 2020], Available on: online, 2020, “Results for trimovate” [Accessed 8th of January 2020], Available on:  

Assessed by:

Dr Imran Malik, General practitioner
Registration number: GMC: 4741365

Dr Imran Malik studied undergraduate medicine at King's College University in Central London and clinical studies at the prestigious King's College Hospital. He graduated with a MBBS degree in 2000 and went on to gain postgraduate memberships with the Royal Society of Medicine and also General Practice in 2006.