Xyzal is a common form of antihistamine that can be used for a range of different treatments, and in combination treatments with other medications or therapies. Antihistamines are a group of drugs that work by suppressing the amount of "histamine", a natural chemical in your body. More information

A doctor will review your order and write you a prescription, if appropriate. This prescription is then forwarded to a pharmacy. The pharmacy will have your medicine delivered to you within one to three working days. Read more about this process here.

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Xyzal is an antihistamine medication containing the active ingredient Levocetirizine. This substance is prescribed to treat a range of conditions caused by the natural chemical "histamine" within the human body. Xyzal may reduce symptoms like runny noses, hives, itching, irritated eyes and more.  

What is Xyzal? 

Xyzal is a common form of antihistamine that can be used for a range of different treatments, and in combination treatments with other medications or therapies. Antihistamines are a group of drugs that work by suppressing the amount of "histamine", a natural chemical in your body. By reducing the amount of histamine that you have in your system at any given time, Xyzal can reduce your exposure to the symptoms of allergic reactions caused by seasonal or everyday substances.  

When prescribed by a doctor, Xyzal is often used to treat common but unthreatening conditions like dry eyes, coughing, sneezing, watery eyes, and even rashes or itching. It is important not to self-treat with Xyzal before you have had a consultation with a doctor. There may be another form of antihistamine that is better suited to your needs. 

When is Xyzal used? 

Xyzal is one of the antihistamines often prescribed by doctors to relieve the symptoms of allergies. The issues that Xyzal can help to overcome include things like a runny nose, itching nose or eyes, sneezing, and watery eyes.  

In the human body, the chemical "histamine" is produced when you encounter something that triggers an allergic reaction in you. For some people, this might mean that you produce more histamine when you're exposed to dust, pollen, or even pet dander. The histamine in your system attempts to drive the substance out of your body by causing your eyes to water or forcing you to sneeze. You may even see itchy spots on your skin called hives.  

An allergic reaction can be caused by a wide variety of triggers. Your doctor can conduct a test to find out what causes your allergies before prescribing Xyzal, so you know what triggers to avoid whenever possible. This medication works by reducing the way that your body responds to histamine. Although Xyzal cannot prevent hives from happening, or treat a serious allergic reaction, it can help significantly with reducing your risk of symptoms when you have an allergy attack.  

Most of the time, Xyzal works quickly to tackle allergy symptoms. You may notice that your symptoms begin to reduce within 30 minutes of taking your tablet. 

How do you use Xyzal? 

Xyzal is available in tablet form. If you're taking this medication for allergies, it's important to read and follow all of the instructions provided within the product packaging before you begin using the tablets. You can also ask your doctor for extra guidance if you're not sure how to make the most out of this medication. A pharmacist can be a good source of information too.  

Your doctor will ask you to take Xyzal by mouth, usually with a drink of water. You can take this medication with or without food, and it's often taken once per day, as the effects last up to 24 hours. Taking Xyzal with food may reduce your risk of suffering from gastrointestinal side effects.  

Xyzal is best taken on an evening before you go to bed. This is because, like other antihistamines, it has the potential to cause drowsiness. The amount you will be required to take will depend on a lot of factors, including the severity of your symptoms, and your age. Xyzal can be used to treat acute complaints, or it can be taken on a regular basis to help prevent against allergy. For instance, you may use this medication to cope with having pets in the house when you're allergic to their dander.  

What dosages are available? 

The dose of Xyzal that you need to take will be chosen by your doctor after a thorough examination of your condition and medical background. Usually, the most common dose for Xyzal is one tablet, taken once per day, or when necessary. This substance is not suitable for children under the age of 6. Do not take more or less of this medication than your doctor recommends. 

If you take more than one tablet of Xyzal within a 24-hour period, or you believe that you have accidentally overdosed, contact an emergency healthcare provider immediately. 

What are the side effects of Xyzal? 

Xyzal can cause a number of side effects, or none at all, depending on your medical background. All drugs have the power to cause side effects, but your doctor will consider this risk when prescribing a medication and will only give you the drugs that seem to be right for your needs. If your doctor has directed you to begin this medication, it's because they believe that you are not at serious risk.  

Common side effects of Xyzal include: 

  • Cough 
  • Fever 
  • Tiredness 
  • Dry mouth 
  • Drowsiness 

These side effects may pass on their own over time as your body adjusts to the medication. If they persist or get any worse, speak to a doctor about your options.  

If you experience any serious side effects after taking Xyzal, including difficulty going to the bathroom (urinating) or severe feelings of weakness, tell a doctor or medical professional immediately. 

A very significant allergic reaction to Xyzal doesn't happen very often. However, tell a medical health professional immediately if you notice a rash, itching, or swelling, particularly around the tongue, throat, or face. You should also contact a doctor if you have trouble breathing or severe dizziness. 

When shouldn't you uses Xyzal? 

Before you begin using Xyzal it is important to discuss your medical history with your doctor. This will help your healthcare professional to decide whether Xyzal is the suitable treatment for you, or whether another medication might be safer. You should not take this medication if you are allergic to any of the ingredients within it, including levocetirizine. Avoid taking this drug if you are allergic to hydroxyzine or cetirizine.

Before using Xyzal, tell your doctor if you have any history of problems with your kidney, including kidney disease, difficulty urinating, or other issues that might stop you from urinating, like an enlarged prostate. This drug may also make you feel drowsy. This is a common side effect of anti-histamines. Keep in mind that other substances like cannabis and alcohol can make this condition worse. Avoid alcohol when taking Xyzal until you know how you respond to the medication.  

If you are taking the liquid version of Xyzal, then it may also contain substances like aspartame and sugar. It is worth avoiding this option if you have diabetes or another condition that might make it dangerous to have additional sugars in your diet. Your doctor may simply ask you to monitor your blood sugar levels more carefully.  

Does Xyzal interact with any other medications? 

Xyzal and many other drugs can easily interact poorly with other medications that you are already taking. Before you begin using any new medication, make sure that your doctor is aware of all the substances that you may already be using. This includes any over-the-counter and non-prescription medications, prescription medications, recreational drugs, supplements, herbal pills and vitamins. Do not start or change the dosage of any new medication without the approval of your doctor.  

Make sure that your doctor is aware if you are taking any other products with Xyzal that might cause drowsiness. This includes opioid pain relievers like codeine, as well as alcohol, drugs for anxiety or sleep, and muscle relaxants like carisoprodol. It is not a good idea to take Xyzal alongside other antihistamine medications, as this can place too much of the same substance into your blood stream at once and increase your chances of dangerous side effects.  

When using Xyzal, check the labels on any medications that you're taking for temporary ailments, like coughs and colds. Often, these medications can also cause antihistamines and other ingredients that cause drowsiness. Your doctor or pharmacist will be able to advise you on whether it's safe to use certain products. Do not use this medication with any antihistamines that you apply to the skin or use in the form of a spray, as this can also increase your risk of side effects.  

Xyzal contains the active ingredient levocetirizine, which is very similar to cetirizine and hydroxyzine. It is important not to use these additional medications when using Xyzal.  

Where can you buy Xyzal? 

Xyzal is available to purchase from registered pharmacies in the EU with an approved prescription. You can purchase this medication at a pharmacy in your local area or instruct us to have this drug ready for you to collect at a registered pharmacy. With prescription medications we can also arrange for a consultation with a genuine EU doctor on your behalf.  

Can you get Xyzal without a prescription?  

In the EU you cannot get Xyzal without a prescription. It is important to speak to your doctor about your condition and reasons for needing Xyzal before you use this medication. If this substance is not suitable for you, then most doctors will be able to recommend an alternative.  




UCB Pharma Limited, EMC,, online, 2019, Xyzal 5mg tablets, [Accessed on the 22nd of August 2019], Available at: 

RXlist, online, 2019, Xyzal, [Accessed on the 22nd of August 2019], Available at: 

eMedicine Health, 2019, online, Levocetirizine (Xyzal), [Accessed on the 22nd of August 2019], Available at: 

Assessed by:

Dr Imran Malik, General practitioner
Registration number: GMC: 4741365

Dr Imran Malik studied undergraduate medicine at King's College University in Central London and clinical studies at the prestigious King's College Hospital. He graduated with a MBBS degree in 2000 and went on to gain postgraduate memberships with the Royal Society of Medicine and also General Practice in 2006.