Indivina is a hormone preparation that relieves menopausal symptoms. Indivina tablets contain the active ingredients estradiol and medroxyprogesterone, which are two female sex hormones. More information

A doctor will review your order and write you a prescription, if appropriate. This prescription is then forwarded to a pharmacy. The pharmacy will have your medicine delivered to you within one to three working days. Read more about this process here.

Instruction costs
Service – Instruction costs

Indivina 1 mg/2.5 mg 84 tabl. + Consult + Service fee

Indivina 1 mg/5 mg 84 tabl. + Consult + Service fee

Indivina 2 mg/5 mg 84 tabl. + Consult + Service fee

Patient Leaflet(s)

What is Indivina?

Indivina is a hormone preparation that relieves menopausal symptoms. Indivina tablets contain the active ingredients estradiol and medroxyprogesterone, which are two female sex hormones. Indivina is prescribed as hormone replacement therapy (HRT), also called hormone therapy (HT), in menopausal women. Indivina is a prescription-only medicine.

What is Indivina used for?

Indivina is used to relieve menopausal symptoms, including:

  • Hot flushes;
  • Vaginal dryness;
  • Difficulty falling asleep or staying asleep;
  • Osteoporosis (decrease in bone mass and density);
  • Night sweats;
  • Mood swings.

The above symptoms are caused by a decrease in the production of oestrogen. HRT restores hormonal balance and so reduces or eliminates these symptoms. Indivina is particularly suitable for women with an intact womb who have stopped having periods for some time.

How to use Indivina

Indivina tablets should be swallowed whole, without chewing, with plenty of liquid. Try to take the tablets at the same time each day. Unless the doctor advises otherwise, Indivina is taken continuously. This means there is no tablet-free week. When you finish all 28 tablets you start with a new blister the following day. Indivina will not cause a monthly withdrawal bleed. However, you may experience spotting or breakthrough bleeding during the first few months of treatment. Do not use this medicine for more than two years without consulting a doctor.


Unless otherwise advised by a doctor, the usual dose in adult women is:

  • one tablet once daily.

Always follow the prescription exactly - never use more or less than the doctor recommends. Read the package leaflet before use.

Side effects

Indivina tablets may cause side effects. The following are some of the side effects that are known to be associated with this medicine:

  • Headache;
  • Breast tenderness or soreness;
  • Gastrointestinal symptoms such as stomach ache and nausea;
  • Loss of libido;
  • Mood swings;
  • Weight gain due to fluid retention.

Consult a doctor if the side effects are persistent. For more information on side effects, see the package leaflet. The package leaflet will also tell you that all women using HRT have a slightly increased risk of serious side effects such as cancer and thrombosis compared with women who don't use HRT.

When not to use Indivina

Indivina is not suitable for everyone. Do not use this HRT preparation if:

  • You are allergic to estradiol, medroxyprogesterone or any other of its ingredients;
  • You have a known or past history of breast cancer or cancer in which growth of the cancer is stimulated by oestrogen (e.g. endometrial cancer);
  • You have vaginal bleeding of unknown cause;
  • You have an overgrowth of the lining of the womb (endometrial hyperplasia);
  • You have a blood clot in a vein (thrombosis) or the lungs (pulmonary embolism) or a history of this;
  • You have a blood disorder or liver disease.

Consult a doctor on the use of Indivina if you have a health condition that is not listed above or are currently on medication.

Pregnancy/driving ability/alcohol

This medicine is intended for women who are no longer in the fertile age bracket. The following advice applies to women who don't fall within this group:

  • Indivina tablets should not be used during pregnancy and while breastfeeding.

Warning: this medicine does not protect against pregnancy. If necessary, you should use a contraceptive of some kind as a precaution. Indivina does not affect your reaction time or interact with alcohol.