Perindopril is a medication used for lowering blood pressure in people with hypertension. This substance belongs to a group of drugs called ACE inhibitors. They work by dilating and relaxing the blood vessels within the body to ensure that your blood can flow more freely. More information

A doctor will review your order and write you a prescription, if appropriate. This prescription is then forwarded to a pharmacy. The pharmacy will have your medicine delivered to you within one to three working days. Read more about this process here.

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Perindopril is a substance used to treat hypertension or high blood pressure. In patients with high blood pressure, this substance can help to reduce the risk of kidney problems, heart attacks, strokes, and other serious complications. Perindopril may be used in conjunction with other treatments for patients with heart disease.  

What is Perindopril? 

Perindopril is a medication used for lowering blood pressure in people with hypertension. This substance belongs to a group of drugs called ACE inhibitors. They work by dilating and relaxing the blood vessels within the body to ensure that your blood can flow more freely. Because they make it easier for blood to flow around your body, ACE inhibitors can also be prescribed to people following a heart attack to reduce their risk of further cardiac damage. Perindopril can reduce the risk of future heart attacks and strokes in people with high blood pressure or other conditions with their heart and circulatory system. This medicine comes in tablet form and is only available to take on prescription. In some cases, Perindopril may be used in combination with other medications for high blood pressure.  

When is Perindopril used? 

Perindopril is used primarily for the treatment of hypertension, or high blood pressure. Although high blood pressure doesn't necessarily cause any symptoms by itself, it can increase your risk of complications like heart attacks, strokes, and even kidney failure. Perindopril helps to reduce this risk and ensure that you can live a longer, healthier life. In some cases, Perindopril may be prescribed to patients to reduce their risk of a fatal heart attack if they have coronary artery disease or another form of heart failure. This drug may be prescribed after a heart attack to improve blood flow in the body. Perindopril belongs to a class of medications called ACE inhibitors and can be used alongside other medications for the treatment of hypertension.  

How do you use Perindopril? 

Unlike some other treatment options for hypertension, Perindopril is only available in tablet form. You will need to read the leaflet provided by your doctor, or the information that is included in the medication packet when taking this drug. Make sure that you check the instructions for this medication every time you get a refill. Perindopril works best when it is used regularly every day. Take this medication by mouth, according to the dosage prescribed by your doctor. This usually means taking a tablet once a day. You do not need to take this medication with food, but some people find that they are less likely to suffer from stomach aches and nausea if they take it before a meal. Ideally, to ensure that you take Perindopril at the same time each day, it's a good idea to set an alarm when you're taking it. This will also reduce your risk of side effects when you miss a dose. Your doctor may start you on a low dose of Perindopril and increase the amount that you take over time. Make sure that you continue taking this medication even if you begin to feel better.  

If you miss a dose of Perindopril accidentally, you can take the tablet as soon as you remember. If you don't remember until the next day, skip the dose if it is too close to your usual medication time. Do not take an extra dose of Perindopril at the same time as your regular dose to make up for a forgotten pill.  

What dosages are available? 

Perindopril is available in 2mg, 4mg and 8mg tablets. The dose that you are given will depend on why you're taking the medication, and your previous response to treatment. To decide what the correct dose is for you, your doctor will check your blood pressure and discuss your medical history with you. You may need regular blood pressure tests when taking this drug. Perindopril comes in the form of Perindopril erbumine or Perindopril arginine. Both drugs work in a similar fashion, but the dose might vary. For instance, when you're taking Perindopril erbumine, the usual starting dose is between 2mg and 4mg a day. Your doctor may increase this to up to 8mg if you are recovering after a heart attack.  

If you are taking Perindopril arginine, then the starting dose is typically between 2.5 and 5mg per day. Your dose may be increased over the course of a few weeks to reduce the risk of side effects. The dose for patients after a heart attack can be increased to 10mg per day. If you accidentally take too many pills and are concerned that you may have been exposed to an overdose, contact the emergency services immediately for help. Always notify a doctor in the event of a possible overdose.  

What are the side effects of Perindopril? 

All medications can cause side effects, including Perindopril. Most people will not experience any severe side effects with this drug. However, you may notice that you get a few symptoms initially that get better over time as your body adjusts to the medicine. The most common side effects of Perindopril will disappear by themselves. These include a dry and tickly cough, feeling lightheaded or dizzy, and suffering from headaches. Some patients taking Perindopril get a mild skin rash and may have vomiting and diarrhea. You may also notice slightly blurred vision.  

If you experience any more severe side effects when using Perindopril, you should contact your doctor or an emergency healthcare provider immediately. Perindopril can sometimes cause liver problems, which could appear in the form of yellowing in your eyes or skin. If you notice that you are paler than usually, are bleeding from the gums, have a sore throat, or are getting regular infections, this could be a sign of a bone marrow or blood disorder. Tell your doctor if you're experiencing any heart or lung problems which appear with symptoms like wheezing or pain in your chest, a faster heart rate or trouble breathing. An inflamed pancreas may also occur when taking Perindopril which appears in the form of severe stomach pain. Although Perindopril can be used to reduce your risk of kidney problems, it may also cause kidney issues in very rare circumstances. If you notice blood in your urine, problems with going to the bathroom, or swollen ankles, contact your doctor.  Severe allergic reactions are not common with Perindopril, but they are possible. Do not hesitate to seek medical assistance if you have swollen lips, a swollen throat or tongue, trouble breathing, or you feel extremely dizzy.  

When shouldn't you use Perindopril? 

Perindopril is available for adults over the age of 18 and over. However, not everyone will be suitable for this medication. To make sure that this drug is safe for you, make sure you tell your doctor about your complete medical history, including whether you have ever had an allergic reaction to this substance, or any other ACE inhibitors like it. You should also speak to your doctor if you have ever had any heart, liver or kidney problems, or are having treatment for blood filtration. If you have unstable blood pressure, or low blood pressure, then your doctor may suggest another medication. If you are on a low-salt diet, then Perindopril may not be suitable for you. Additionally, Perindopril is not recommended for people with blood problems that lower their white blood cell count.  

Does Perindopril interact with any other medications? 

Perindopril may interact negatively with other medications. This is why it is always important to tell your doctor about any other drugs that you are taking before you begin using Perindopril. Make sure your doctor is aware of all of the substances that you might be using, including any supplements, herbal substances, or drugs that you can buy over the counter.  Perindopril may not be suitable to use with other ACE inhibitors, as they may cause your blood pressure to become too low, which can be dangerous too. Additionally, lithium, gold injections, and certain drugs that weaken the immune system can be dangerous when taken alongside Perindopril. This substance can increase the level of potassium in your blood, which means that it is not suitable to take the medication alongside any other supplements or substances that include potassium. This may include certain birth control pills. Perindopril can cause a very serious reaction when you are getting injections for a wasp or bee sting allergy.  

Where can you buy Perindopril? 

Perindopril is available to buy from any pharmacist online or offline. It's not available over the counter, as you will need a consultation with a doctor to ensure that this medication is right for you. Make sure that you speak to a registered medical professional before ordering this substance to ensure that it's safe for you to use.  

Can you get Perindopril without aprescription?  

Perindopril is not available without a prescription. We can arrange for you to have a consultation with a registered healthcare professional where you can discuss your condition and medical history. The healthcare professional will them determine whether it is safe to give you a prescription for Perindopril based on your symptoms and family history. If Perindopril is not suitable for you, then your doctor may be able to suggest an alternative form of treatment.  




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Assessed by:

Dr Imran Malik, General practitioner
Registration number: GMC: 4741365

Dr Imran Malik studied undergraduate medicine at King's College University in Central London and clinical studies at the prestigious King's College Hospital. He graduated with a MBBS degree in 2000 and went on to gain postgraduate memberships with the Royal Society of Medicine and also General Practice in 2006.