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Avomine

Avomine is a medication containing the drug promethazine – a sedating antihistamine used for a range of reasons. This substance can treat or prevent feelings of sickness or nausea, and is commonly recommended for people who experience these symptoms because of vertigo or travel. Avomine may also be used to relieve allergic reactions caused by hay fever and allergic skin rashes, but it can cause a sedative effect. It may sometimes be used to promote sleeping in adults with severe insomnia, but it is recommended that it should not be used for this reason in the long term. Avomine is the brand name for a medication containing the active ingredient promethazine, an antihistamine which may ease allergy symptoms. Avomine is also effective at calming the receptors in the brain which cause vomiting. It can reduce feelings of nausea and sickness.

What is Avomine?

Avomine is a medication containing the drug promethazine – a sedating antihistamine used for a range of reasons. This substance can treat or prevent feelings of sickness or nausea, and is commonly recommended for people who experience these symptoms because of vertigo or travel. Avomine may also be used to relieve allergic reactions caused by hay fever and allergic skin rashes, but it can cause a sedative effect. It may sometimes be used to promote sleeping in adults with severe insomnia, but it is recommended that it should not be used for this reason in the long term.

When is Avomine used?

Avomine tablets are typically used to prevent vomiting and nausea related to conditions such as motion sickness and vertigo. Some doctors will also prescribe them to prevent nausea after surgery. In some cases, you may be given Avomine tablets to treat allergic symptoms such as rashes, a runny nose and itching.

For very short periods of time, they can be used to help certain pain relievers work better, or to help you remain relaxed or get more sleep after surgery. They have also been used to help with the common cold and to stop a runny nose. If you are not using Avomine tablets for motion sickness, it may be dangerous to take them for other reasons. Avoid taking any medication without guidance and advice from a doctor or pharmacist.

How do you use Avomine tablets?

Your doctor or pharmacist will be able to provide you with advice on how to use Avomine tablets. You can also find instructions written on the printed leaflet inside your medication packet. This leaflet will contain a full list of the side effects common when taking Avomine tablets. Make sure that you follow the instructions given by your doctor or pharmacist exactly. You may need to take multiple doses in a single day depending on your reasons for taking this medication.

If you are using Avomine tablets to prevent travel sickness, you will usually be asked to take the first dose at bedtime on the night before you travel. You may also be able to take an additional dose on the day that you travel, if necessary. Avomine tablets can be taken before or after meals and should be swallowed with water. If given in liquid form for a child, it is important to follow the instructions for dosage on the bottle very carefully. The majority of people will only need to take Avomine tablets for a short period of time when they are experiencing symptoms. You can stop taking Avomine tablets after your symptoms subside unless your doctor suggests otherwise.

Avomine tablets should not be taken for more than a few days to help with sleeping or relaxation problems, as they may lead to addiction or other negative side effects.

What dosages are available?

The dose of Avomine tablets you will need to take will usually be advised by your doctor, or you can seek advice from your pharmacist. If you are taking this medication for flight sickness, then a 25 mg tablet will be the most common dosage, taken once on the night before travel, and once on the morning of the travel.

If you are taking Avomine tablets for other purposes, such as to prevent sickness after surgery or to overcome hay fever symptoms, you may need to take your medication more regularly. Patients taking Avomine tablets for reasons other than motion sickness should ask their doctor for advice on how to manage their dosage. No more than one tablet should be taken every eight hours. It is important not to take Avomine tablets for extended periods of time.

What are the side effects of Avomine?

Like any medication, Avomine can cause some side effects. If you notice any unusual symptoms occurring after you take Avomine tablets, stop taking them and tell your doctor. Constipation, drowsiness, dizziness, dry mouth, blurred vision and some other issues may occur. If you have dry mouth frequently but wish to continue taking Avomine tablets, you could try chewing sugarless gum, or sucking on ice chips.

If you notice the presence of more serious side effects when taking Avomine tablets, such as fainting, a sudden change in your mood or state of mind, or a slower heartbeat, tell your doctor immediately. Other severe side effects might include uncontrolled or unusual movement, tongue movements, shaking or tremors, bruising or bleeding easily, and difficulty urinating. You should also monitor signs of infection such as a persistent sore throat or fever. If you experience severe stomach or abdominal pain, yellowing eyes or skin, or persistent vomiting when using Avomine tablets, tell a doctor straight away. Get medical help immediately if you experience seizures or shallow, slow breathing.

In very rare conditions, it is possible to experience neuroleptic malignant syndrome when taking Avomine tablets. Get medical help immediately if you have muscle pain, weakness, stiffness or tenderness, a severe fever, confusion, excessive sweating, tiredness, fast or irregular heartbeat, or signs of kidney problems (dark or frequent urine). Severe allergic reactions to Avomine tablets are rare, but tell your doctor if you notice a rash, itching, swelling of the tongue, throat or face, or have trouble breathing.

When should you not use Avomine?

Make sure you tell your doctor or pharmacist about any other medications that you are taking before you use Avomine tablets. This should include prescribed medications, over-the-counter drugs, herbal remedies and supplements. Before using this medication, tell your pharmacist or doctor if you have a history of breathing problems, including sleep apnoea and asthma.

Avomine tablets may not be suitable if you have immune or blood problems, high pressure in the eyes, heart disease, or high blood pressure. They may also be inappropriate for people with certain brain disorders, liver disease, intestine or stomach problems, overactive thyroids or problems with urination, potentially caused by an enlarged prostate.

If you feel dizzy or drowsy when using Avomine tablets, do not drive or operate heavy machinery, and avoid alcoholic beverages that could make these conditions worse. Remember that Avomine tablets may make it harder for you to sweat, making you more likely to experience heat stroke if you get overly warm. Avoid doing things that cause you to feel too hot, such as strenuous exercise. Seek medical help if you have a fever that does not go away.

Avomine may not be ideal for use during pregnancy, as it is unknown whether it passes into breast milk. This should be discussed with your doctor before use. It is generally not advisable to take Avomine tablets if you are pregnant unless advised by your doctor, who will be able to recommend an alternative antihistamine or a different solution to deal with motion sickness.

Does Avomine interact with any other medications?

Avomine tablets may interact with other medications, Before you start taking them, make sure that you speak to your doctor or pharmacist about any other medications you might be taking, including those you bought without a prescription. It is important to talk to your doctor before you begin using new medications with Avomine tablets, to ensure that the combination of drugs is safe.

Avomine tablets are not suitable for anyone taking anti-depressants that are monoamine oxidase inhibitors, such as phenelzine and isocarboxazid. If you have taken those medications in the past 14 days, do not take Avomine. It is also not advisable to take Avomine tablets with other medications used to help you sleep, such as zopiclone, or sedating antihistamines such as hydroxyzine or chlorphenamine. Do not take Avomine tablets when drinking alcohol or using antipsychotic medications such as chlorpromazine. Avoid using this medication with barbiturates such as phenobarbital, or benzodiazepines such as diazepam. Avomine tablets are not suitable for use with heavy-duty painkillers such as codeine and morphine.

You may have an increased risk of side effects when using Avomine tablets if you have them when taking other medications such as hyoscine, antihistamines such as brompheniramine, or anti-nausea medications such as meclizine. Avomine tablets may cause more side effects when used with anticholinergic medications given for Parkinson’s disease, and muscle relaxants. Antihistamines such as Avomine can reduce the effects of the Meniere’s disease medication betahistine, and the histamine given for leukaemia.

Where can you buy Avomine?

Avomine tablets are available to buy online or offline over the counter or with a prescription. Make sure that you speak to a doctor if you are using Avomine tablets for any reason other than motion sickness. It is important to talk to your doctor before using this medication if you are already using any other drugs for any reason, as Avomine tablets can interact with other medications.

Can you obtain Avomine without a prescription?

Avomine is available in some forms over the counter, however it is not a good idea to purchase it without first speaking to a pharmacist or doctor. You will need to discuss your condition with your doctor and any medications you might be taking alongside Avomine tablets. Speaking about your condition with your doctor will help you avoid any dangerous side effects or interactions with other drugs.

References

Actavis UK Ltd, the Electronic Medicines Compendium, 2015, Manufacturer’s PIL, Sominex tablets [Accessed 21 June 2019], available on: http://www.medicines.org.uk/EMC/medicine/21226/XPIL/Sominex+Tablets/

Manufacturer’s PIL, Phenergan® 10 mg Tablets; Sanofi, The electronic Medicines Compendium. [Accessed 21 June 2019], available on: http://www.medicines.org.uk/EMC/medicine/3891/PIL/Phenergan+10mg+Tablets/

Sanofi, Promethazine Hydrochloride, Phenergan 25mg tablets, [Accessed 21 June 2019], available on: https://www.medicines.org.uk/emc/product/5588/pil

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