Menu

Diltiazem

Diltiazem ointment is intended for anal use. It contains the active ingredient diltiazem hydrochloride, which is a type of medicine called a calcium-channel blocker. Diltiazem ointment works by relaxing the blood vessels around the anus. This helps to alleviate anal discomfort, such as pain and itching caused by anal fissures. Diltiazem also promotes blood flow, allowing the healing process to begin.

Diltiazem ointment

Diltiazem ointment is intended for anal use. It contains the active ingredient diltiazem hydrochloride, which is a type of medicine called a calcium-channel blocker. Diltiazem ointment works by relaxing the blood vessels around the anus. This helps to alleviate anal discomfort, such as pain and itching caused by anal fissures. Diltiazem also promotes blood flow, allowing the healing process to begin.

Table of Contents

What is Diltiazem?

When is Diltiazem used?

How is Diltiazem used?

What doses are available?

What are the side effects of Diltiazem?

When not to use Diltiazem?

Can Diltiazem be used in combination with other medicines?

Where can I buy Diltiazem?

Can I buy Diltiazem without a prescription?

Sources

What is Diltiazem?

Diltiazem ointment is used to treat anal discomfort and fissures. The ointment contains the active ingredient diltiazem hydrochloride. Diltiazem relaxes the anal sphincter, which helps to alleviate pain and itching. Diltiazem also promotes blood flow, which allows the lining of the anal canal to heal more quickly.

When is Diltiazem used?

Diltiazem ointment is prescribed as a treatment for anal fissures, small rips or tears in the lining of the anal canal. Signs and symptoms of an anal fissure include:

  • Itching.
  • Pain and/or burning sensation.
  • Bleeding during or after bowel movements.
  • Cramping of the anal sphincter.

The symptoms typically increase with or following a bowel movement.

Most cases of anal fissures are caused by constipation. Straining during bowel movements and passing hard stools increase the risk of tearing. Other possible causes of anal fissures include Crohn’s disease and anal sex.

You can prevent anal fissures by keeping stools soft. It helps to eat a well-balanced diet with plenty of fibre, and to drink plenty of water. Exercise also promotes regular bowel movements. Do not avoid going to the toilet when you feel the need. Use soft toilet paper and ensure good hygiene by cleaning the anus with lukewarm water after a bowl movement to prevent further irritation.

Anal fissures that last for six weeks or more are called chronic anal fissures. Chronic fissures are typically treated with Diltiazem ointment. The ointment reduces itching and aids the healing process.

How is Diltiazem used?

It is important to follow the instructions given by your doctor or pharmacist when using this medicine. The general guidelines for use are as follows:

  • Use Diltiazem ointment twice a day every day (morning and evening).
  • Wash and dry the anus and apply the ointment to the painful or itchy areas. Wash hands after use. A finger covering such as a disposable glove or finger cot may be used to apply the cream (you can get finger cots from a local pharmacy).
  • Continue using this medicine until the anal fissures have healed completely. Depending on the severity of the anal fissure, it may take several weeks or months of treatment for the fissure to heal. The pain symptoms are typically relieved within two weeks of treatment.
  • If you forgot to apply the ointment, you may do so as soon as you remember, unless it is almost time for your next scheduled dose.
  • Consult a doctor if the symptoms are not relieved after a few weeks.
  • Diltiazem has a limited shelf life. After opening, the ointment can be kept for a few weeks (see the package leaflet).

See the package leaflet for more information on the use of Diltiazem.

What doses are available?

One gram of Diltiazem ointment contains 20 mg diltiazem hydrochloride. Unless otherwise prescribed, the usual dose is:

  • Adults: apply about a fingertip of ointment in and around the anus twice daily.

Read the package leaflet before use.

What are the side effects of Diltiazem?

Diltiazem ointment may cause side effects, including:

  • Irritation in and around the anus (burning sensation or itching).
  • Dizziness or headache (rare).
  • Allergic reactions (rare).

For more information on possible side effects of Diltiazem ointment, see the package leaflet. Consult a doctor or pharmacist if these or other side effects are severe.

When not to use Diltiazem?

Diltiazem ointment is not suitable for everyone and should not be used if:

  • You are allergic to diltiazem hydrochloride or any other ingredient in this medicine.

This medicine should not be used if you are pregnant, breastfeeding or trying to conceive. Check with your doctor or pharmacist for other treatment options.

For more information on this subject, see the package leaflet.

Can Diltiazem be used in combination with other medicines?

It's important to tell your doctor or pharmacist what medicines you are already taking before you start using Diltiazem ointment to make sure that the combination is safe. For more information on possible interactions, see the package leaflet.

Where can I buy Diltiazem?

Diltiazem is only available at pharmacies or online pharmacies.

Can I buy Diltiazem without a prescription?

Diltiazem is a prescription-only medicine. This means you need a prescription from a registered doctor to obtain it.

Sources

GMP Apotheek de Magistrale Bereider. (2018, October). Package leaflet Diltiazem HCl 2% Gel / 2% Vaseline-cetomacrogol cream. www.apotheekkennisbank.nl. https://www.apotheekkennisbank.nl/geneesmiddelen/bijsluiters/diltiazem-gmp-apotheek-de-magistrale-bereider-vaselinecetomacrogolcreme-2

Royal Dutch Pharmaceutical Society. (2019, 11 September). Topical use of Diltiazem. Apotheek.nl. https://www.apotheek.nl/medicijnen/diltiazem-op-de-huid#!

Dutch Digestive Diseases Foundation. (n.d.). Anal fissure. Consulted on 23 March 2021 on https://www.mlds.nl/ziekten/anaal-fissuur/

Dutch National Health Care Institute. (n.d.). Diltiazem (for treatment of anal fissures). FK Online. Consulted on 23 March 2021 on https://www.farmacotherapeutischkompas.nl/bladeren/preparaatteksten/d/diltiazem__bij_anale_fissuur_#samenstelling

Patient Leaflet(s)
Back to top