Timodine is an anti-inflammatory and anti-fungal cream typically used for skin infections, allergic reactions, itchy skin rashes, and itchy reactions to bites. It may also be used for skin irritation and other conditions not listed in this guide. More information

A doctor will review your order and write you a prescription, if appropriate. This prescription is then forwarded to a pharmacy. The pharmacy will have your medicine delivered to you within one to three working days. Read more about this process here.

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Patient Leaflet(s)

Timodine is a cream-based treatment designed to treat inflamed skin conditions where there may also be a fungal infection caused by the fungus Candida Albicans. Infections treated with Timodine may include candida interigo, nappy rash, eczema, and more. There are multiple substances included in Timodine to make it effective, including Hydrocortisone, a topical corticosteroid, Benzalkonium, an antiseptic, Nystatin, an antifungal, and Dimeticone, a water-repellant fluid.  

What is Timodine? 

Timodine is an anti-inflammatory and anti-fungal cream typically used for skin infections, allergic reactions, itchy skin rashes, and itchy reactions to bites. It may also be used for skin irritation and other conditions not listed in this guide.  

The standard 30g Timodine cream contains a combination of Benzalkonium chloride, hydrocortisone, dimeticon, and nystatin. The combination of these four active ingredients works to eliminate skin issues in a number of ways. For instance, the hydrocortisone is a topical corticosteroid which prevents the skin cells from releasing inflammatory substances. This reduces redness, swelling and itching. Nystatin is a form of antifungal medication that causes holes to appeal in the membranes of yeasts and fungi. This eventually kills the fungi and the infection. The Benzalkonium chloride in Timodine is an antiseptic, which eliminates the bacteria which can cause an infection to persist. Additionally, the Dimeticone is a water-repellant fluid which stops the skin from absorbing moisture, helping to reduce the growth of fungi.  

When is Timodine used? 

Timodine cream can be used for a variety of reasons. Typically, it is intended to control, treat and prevent conditions ranging from skin infections, to vaginal infections, inflammation of the skin, allergic reactions, and skin irritation.

Other uses for Timodine include: 

  • Scaling of the skin 
  • Antiseptic 
  • Preservative for certain drops 
  • Insect bite reactions 
  • Itchy rashes 
  • Skin chafing 
  • Indigestion 
  • Hormonal conditions 
  • Blood diseases 
  • Inflammatory skin disorders 
  • Breathing problems 
  • Conjunctiva and cornea infections 

How do you use Timodine? 

When your doctor prescribes a substance like Timodine, he or she will also give you instructions on how you should be using it. It's important to take your doctor's advice seriously. If you have any queries, you can contact your doctor before using the cream, or read the patient leaflet included in the box. Usually, this medicine will be applied directly to the problematic or inflamed area of skin.  

Because it's cream based, Timodine can be applied topically to the skin in a thin layer. You will need to rub it gently into the skin, without irritating the epidermis. Most doctors will ask you to use Timodine three times a day, although it's important to make sure that you don't use this substance more often than intended. Do not apply additional cream if you feel as though Timodine isn't having the desired effect. 

Wash your hands after using Timodine and avoid contact with your eyes. Make sure that your skin is clean, dry and not exposed to any other substances before and after using Timodine. If you've recently had a bath, give your skin chance to dry first. Unless you're told to use Timodine for a specific period of time, limit your use to no more than 7 days. Using this medication for long periods of time can increase your risk of side effects. Additionally, extended use can lead to the cream becoming ineffective, or you becoming allergic to it.  

If you accidentally swallow this medicine, contact your doctor immediately. Timodine can cause diarrhea, nausea, vomiting, and other issues. 

What dosages are available? 

Timodine comes in a 30mg tube. Unless otherwise prescribed by a doctor, the usual dose for adults and children is a single "thin" layer applied to the affected area of skin three times each day. Young children and adults using this medication should carefully follow the instructions of their doctor. If you miss a dose of Timodine, apply it on the next scheduled application. Do not use extra medication to make up for the missed dose. If you apply Timodine at the same time as other skin medications, leave several minutes before applying the next treatment.  

A fingertip length of cream should generally be enough for a single inflamed area. The thin covering will be enough to have the desired effects.  

What are the side effects of Timodine? 

Risks of significant side effects when using Timodine are very low. However, there is a chance that you may experience negative outcomes when using Timodine cream. The side effects listed here are possible but will not occur in all cases. Additionally, this is not necessarily a full list of side effects. If you experience any negative outcomes when using Timodine, make sure that you seek the advice of your doctor immediately, and stop using the medication until you know more.  

Possible side effects include: 

  • Allergic contact dermatitis 
  • Vomiting 
  • Paralysis of respiratory muscles 
  • Convulsions 
  • Restlessness 
  • Muscular weakness 
  • Dyspnoea 

Timodine cream can, in very rare circumstances, lead to severe allergic reactions. If you notice side effects like itching, rashes, or trouble breathing, contact a doctor immediately. Seek emergency help if you experience any swelling in the face, neck, or jaw. Some people taking Timodine will experience minor skin irritation when the cream is applied. You might notice instances of itching, stinging, redness, or irritation. If these problems occur, or persist, stop using Timodine, and see your doctor.  

If Timodine is used for excessive periods of time underneath dressings or applied to raw skin and large areas of skin, it can also cause additional side-effects common with topical steroids. For instance, you may experience loss of pigmentation, hair growth, stretch marks, or skin thinning. These outcomes are very rare with a mild steroid such as Timodine  

When shouldn't you use Timodine? 

As a relatively mild form of medication, Timodine will be perfectly safe for most people to use. However, it will not be appropriate for all patients. Before you begin using Timodine, it is important to discuss your options carefully with your doctor and discuss all of your current medications in detail. Make sure that your doctor is aware if you are allergic to any of the ingredients included in Timodine. You should also consult your doctor before taking Timodine if you are suffering from a fungal infection in your lungs. Timodine should be used without any plasters or dressings over the cream, and it is important to avoid using machinery or driving if you feel dizzy when using this medication. Timodine is not appropriate to be used by people who are pregnant or breastfeeding.  

Take special care using Timodine for long periods of time, as this can reduce its effectiveness. You should also not use this substance on broken or raw skin without the insight of your doctor. Timodine may not be appropriate for the elderly, newborn babies, or people with certain skin conditions, such as pruritis. Timodine is not intended for use with people who have liver disease. If you have a history of liver problems, or people in your family have issues with liver disease, make sure your doctor is aware of this before taking this medication.  

Does Timodine interact with any other medications? 

Timodine may interact with other medications and make those substances less effective. It is also possible for medications to interact with Timodine and make it less effective. Before you begin taking Timodine, make sure that you let your pharmacist or doctor know about any other substances that you are taking - particularly if you're taking corticosteroids bought with a prescription.  

If you need to continue using medications at the same time on the same area of the skin as you are applying Timodine, leave plenty of time between applications to stop the substances from mixing. Tell your doctor if you are taking any vitamins or herbal supplements when using this substance.

There are various forms of medication that may interact with Timodine, including: 

  • Amobarbital 
  • Ascorbic acid 
  • Aminoglutethimide 
  • Amphotericin B 
  • Carbamazepine 
  • Dextranomer 
  • Carboxymethylcellulose 
  • Furosemide 
  • Gentamicin 

In some cases, it's possible for Timodine to interact negatively with aspirin. Avoid using aspirin unless your doctor tells you that you can do otherwise. If you want to apply moisturizers or powders after using Timodine, make sure that you wait at least thirty minutes before or after using Timodine.  

Where can you buy Timodine? 

Timodine is available to be purchased in a range of online and offline pharmaceutical stores. Crucially, you will need a prescription and guidance from your doctor to use this medication. It is dangerous to use Timodine for extended periods of time, which means you should not use it for any longer than 7 days without the advice of your doctor. Do not use someone else's dose of Timodine without guidance from your doctor.  

Can you get Timodine without a prescription?  

Timodine is only available with a prescription. You will need to speak to a doctor about your condition and go through a full medical checkup to ensure that Timodine is right for you. Getting Timodine with a prescription is the only way to make sure that you are getting the treatment that is appropriate for your condition. Using a prescription to get Timodine will also reduce your risk of any dangerous side effects or contradictions with medications that you may already be taking.  




Conforma N.V., Belgium, Timodine Cream Patient leaflet, online EMC, 2017 [Accessed on the 20th of June 2019], Available at: https://www.medicines.org.uk/emc/product/203/pil 

Drugs.com, online, Timodine Cream Patient Information Leaflet, Alliance Pharma, UK, [Accessed on 20th of June 2019], Available at: https://www.drugs.com/uk/timodine-cream-leaflet.html  

Timodine Cream - Uses, Side-effects, Reviews, and Precautions - Alliance Pharma - TabletWise - UK. (n.d.). [Accessed on 20th of June 2019], Available at:  https://www.tabletwise.com/uk/timodine-cream 

Assessed by:

Dr Imran Malik, General practitioner
Registration number: GMC: 4741365

Dr Imran Malik studied undergraduate medicine at King's College University in Central London and clinical studies at the prestigious King's College Hospital. He graduated with a MBBS degree in 2000 and went on to gain postgraduate memberships with the Royal Society of Medicine and also General Practice in 2006.