Fosfomycin (phosphomycin) belongs to a group of antibiotics which have a very broad spectrum of activity. This means that it can be used with a wide variety of infectious bacterial agents. More information

A doctor will review your order and write you a prescription, if appropriate. This prescription is then forwarded to a pharmacy. The pharmacy will have your medicine delivered to you within one to three working days. Read more about this process here.

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Patient Leaflet(s)

What is Fosfomycin? 

Fosfomycin (phosphomycin) belongs to a group of antibiotics which have a very broad spectrum of activity. This means that it can be used with a wide variety of infectious bacterial agents. In combination with other antibiotics, the product is used to treat bacterial infections such as streptococci, staphylococci, pneumococci and enterococci. It is often used as the sole treatment for acute uncomplicated urinary tract infections in women.

The drug works by disrupting important processes in the cell wall construction of the bacteria and therefore destroying them. Fosfomycin is the generic product of Monuril, which is unfortunately no longer available at pharmacies working with 

What is the medicine used for?

Women over the age of 12 take Fosfomycin as the sole means of treatment (monotherapy with Fosfomycin trometamol) in uncomplicated urinary tract infections caused by Fosfomycin-susceptible pathogens. The medicine continues to be used as a combined preparation for other bacterial infections.

Other areas of application include: 
• Infections of the skin and soft tissue 
• Pneumonia and lung abscesses 
• Infections of the central nervous system (e.g. meningitis) 
• Inflammation of the heart's lining (endocarditis)

How to take Fosfomycin

The drug is usually taken orally and is supplied in powder form. Before ingestion, the contents of the bag must first be dissolved in a glass of water. The prepared solution must then be drunk immediately. It is recommended to leave a time interval of two hours between meals. In some cases, and especially in combination therapy, the active ingredient can also be infused directly into the bloodstream.


In monotherapy for the treatment of acute urinary tract infections, women with a body weight over 50 kilograms should take 3000mg of powder. Women with a body weight of under 50 kilograms and children under 12 years may not use the product. In combination therapy, the dose is determined by the attending physician. In principle, the type and severity of the infection are taken into account. In older patients, as well as in people with impaired renal function, the dose must be reduced in most cases. 

Side effects

The most common side effects of Fosfomycin include dizziness, headache and physical weakness. Gastrointestinal complaints such as diarrhoea, nausea and vomiting are also common. A complete overview of the side effects and their likelihood can be found in the patient information leaflet. 

When is it not safe to use this medication? 

Fosfomycin should not be taken if the patient is hypersensitive to the active substance. Patients who have a severely impaired renal function should also avoid this medication. The simultaneous use of metoclopramide, a remedy for nausea and vomiting, must also ensure that there is a time interval between taking both drugs of about two to three hours. In the leaflet, patients will find all the important information and guidelines that must be considered in relation to interactions and contraindications.